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Titre du document / Document title

Diode laser photocoagulation for retinopathy of prematurity : A histopathologic study

Auteur(s) / Author(s)

PARK Paul (1) ; EAGLE Ralph C. (2) ; TASMAN William S. (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Retina Service, Wills Eye Hospital and Thomas Jefferson University, Philadelphia, Pennsylvania, ETATS-UNIS
(2) Department of Pathology, Wills Eye Hospital and Thomas Jefferson University, Philadelphia, Pennsylvania, ETATS-UNIS

Résumé / Abstract

Laser photocoagulation has largely supplanted cryotherapy as an effective treatment for retinopathy of prematurity. This case describes the ocular histopathologic findings of a pair of eyes in a severely premature male infant treated with diode laser photocoagulation for bilateral stage 3 retinopathy of prematurity (ROP) for 360° in zone 1 with severe plus disease. The right eye responded to treatment; the left eye developed persistent vitreous hemorrhage and total retinal detachment. The histopathologic examination of laser burns in the right eye disclosed segmental areas of chorioretinal scarring with retinal atrophy and gliosis, loss of RPE and extensive atrophy of the choroid and its vasculature, which involved both the choriocapillaris and larger vessels. The left eye had iris neovascularization, a chronic organized vitreous hemorrhage and a totally detached retina. The histopathologic findings in an eye of a premature infant with threshold ROP treated with diode laser photocoagulation resembled those reported after transsceral cryotherapy. Diode laser photocoagulation may produce less severe chorioretinal damage.

Revue / Journal Title

Ophthalmic surgery and lasers   ISSN 1082-3069   CODEN OSLAF2 

Source / Source

2001, vol. 32, no1, pp. 63-66 (12 ref.)

Langue / Language

Anglais

Editeur / Publisher

Slack, Thorofare, NJ, ETATS-UNIS  (1995-2000) (Revue)

Mots-clés anglais / English Keywords

Retinopathy ; Premature ; Treatment ; Photocoagulation ; Laser ; Diode ; Chorioretinopathy ; Complication ; Postoperative ; Iatrogenic ; Histopathology ; Case study ; Child ; Human ; Eye disease ; Surgery ; Uvea disease ;

Mots-clés français / French Keywords

Rétinopathie ; Prématuré ; Traitement ; Photocoagulation ; Laser ; Diode ; Choriorétinopathie ; Complication ; Postopératoire ; Iatrogène ; Histopathologie ; Etude cas ; Enfant ; Homme ; Oeil pathologie ; Chirurgie ; Uvée pathologie ;

Mots-clés espagnols / Spanish Keywords

Retinopatía ; Prematuro ; Tratamiento ; Fotocoagulación ; Laser ; Diodo ; Coriorretinopatía ; Complicación ; Postoperatorio ; Iatrógeno ; Histopatología ; Estudio caso ; Niño ; Hombre ; Ojo patología ; Cirugía ; Uvea patología ;

Localisation / Location

INIST-CNRS, Cote INIST : 14946, 35400009386872.0100

Nº notice refdoc (ud4) : 875085

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