Titre du document / Document title

Macular translocation : histopathologic findings in swine eyes

Auteur(s) / Author(s)

ROIG-MELO E. A. ⁽¹⁾ ; ALFARO D. V. ⁽¹⁾ ; HEREDIA-ELIZONDO M. L. ⁽¹⁾ ; YARBROUGH L. M. ⁽¹⁾ ; GAME A. B. ⁽¹⁾ ; APPLE D. J. ⁽¹⁾ ; QUIROL H. M. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Ophthalmology, Hanna Retina Research Center, Storm Eye Institute, Medical University of South Carolina, Charleston, ETATS-UNIS

Résumé / Abstract

PURPOSE. Macular translocation has been proposed as an alternative technique in the treatment of some cases of choroidal neovascularization. The purpose of the paper is to report the histopathologic findings in the retina of swine eyes undergone macular translocation. METHODS. Ten eyes of ten Yucatan pigs underwent posterior pars plana vitrectomy and scleral imbrication to achieve macular translocation. Mattress sutures were preplaced at the equator of the eyes. After a pars plana vitrectomy, balanced saline solution was injected under the temporal retina to produce a retinal detachment. Scleral imbrication was achieved by tightening the mattress sutures. An air-fluid exchange was performed and the eye was filled with sulfur hexafluoride 18%. The eyes were enucleated 2, 4, 8 and 12 weeks after surgery and analyzed under light and electron microscopy. RESULTS. Macular translocation was achieved in all cases. The major findings consist of a minimal decrease in the number of photoreceptors outer segments; also a change in the morphology was noted. This included some degree of loss of vertical alignment and an increase in the interphotoreceptor space. There was a recovery in the morphology of the photoreceptors over time. CONCLUSIONS. Minimal changes in the photoreceptors and retinal pigment epithelium are observed when macular translocation is performed with recovery of these changes over time. Scleral imbrication is an effective technique to achieve translocation of the fovea.

Revue / Journal Title

European Journal of Ophthalmology   ISSN 1120-6721 

Source / Source

2000, vol. 10, n^o4, pp. 297-303 (34 ref.)

Langue / Language

Anglais

Editeur / Publisher

Wichtig, Milano, ITALIE  (1991) (Revue)

Mots-clés anglais / English Keywords

Neovascularization ; Choroid ; Eye ; Membrane translocation ; Macula ; Histopathology ; Pigment epithelium ; Retina ; Photoreceptor ; Treatment ; Technique ; Experimental surgery ; Animal ; Pig ; Artiodactyla ; Ungulata ; Mammalia ; Vertebrata ; Eye disease ; Retinopathy ;

Mots-clés français / French Keywords

Néovascularisation ; Choroïde ; Oeil ; Translocation membranaire ; Macula ; Histopathologie ; Epithélium pigmentaire ; Rétine ; Photorécepteur ; Traitement ; Technique ; Chirurgie expérimentale ; Animal ; Porc ; Artiodactyla ; Ungulata ; Mammalia ; Vertebrata ; Oeil pathologie ; Rétinopathie ;

Mots-clés espagnols / Spanish Keywords

Neovascularización ; Coroides ; Ojo ; Translocación membranaria ; Mácula ; Histopatología ; Epitelio pigmentario ; Retina ; Fotorreceptor ; Tratamiento ; Técnica ; Cirugía experimental ; Animal ; Cerdo ; Artiodactyla ; Ungulata ; Mammalia ; Vertebrata ; Ojo patología ; Retinopatía ;

Localisation / Location

INIST-CNRS, Cote INIST : 22516, 35400009447930.0050