Titre du document / Document title

Evaluating the use of benzodiazepines following recent bereavement

Auteur(s) / Author(s)

WARNER James ⁽¹⁾ ; METCALFE Chris ⁽²⁾ ; KING Michael ⁽³⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Imperial College School of Medicine, St Charles Hospital, London, ROYAUME-UNI
⁽²⁾ Department of Medical Statistics and Evaluation, Imperial College School of Medicine, Hammersmith Hospital, London, ROYAUME-UNI
⁽³⁾ Department of Psychiatry and Behavioural Sciences, The Royal Free and University College Medical School, Royal Free Campus, London, ROYAUME-UNI

Résumé / Abstract

Background There is no evidence to support current advice not to use benzodiazepines after bereavement. Aims To determine the role of benzodiazepines in the management of bereavement. Method We conducted a randomised, double-blind, placebo-controlled evaluation of the use of diazepam after recent bereavement. Participants were randomised to either 2 mg diazepam or identically packaged placebo up to three times daily. The primary outcome measure was the Bereavement Phenomenology Questionnaire. Results Thirty subjects were randomised. No evidence was found of an effect of benzodiazepines on the course of the first 6 months of bereavement (estimated mean difference of combined follow-up assessments=0.3 in favour of placebo; 95% Cl - 6.2 to +6.7). Conclusion We found no evidence of a positive or negative effect of benzodiazepines on the course of bereavement. Declaration of interest This study was funded by the Sir JulesThorn CharitableTrust.

Revue / Journal Title

British journal of psychiatry   ISSN 0007-1250   CODEN BJPYAJ 

Source / Source

2001, vol. 178, n^oJAN, pp. 36-41 (12 ref.)

Langue / Language

Anglais

Editeur / Publisher

Maney, Leeds, ROYAUME-UNI  (1963) (Revue)

Mots-clés anglais / English Keywords

Mourning ; Death ; Spouse ; Sex partner ; Anxiety ; Treatment ; Diazepam ; Low dose ; Tranquillizer ; Psychotropic ; Chemotherapy ; Treatment efficiency ; Toxicity ; Follow up study ; Human ; Benzodiazepine derivatives ;

Mots-clés français / French Keywords

Deuil ; Mort ; Conjoint ; Partenaire sexuel ; Angoisse anxiété ; Traitement ; Diazépam ; Dose faible ; Tranquillisant ; Psychotrope ; Chimiothérapie ; Efficacité traitement ; Toxicité ; Etude longitudinale ; Homme ; Benzodiazépine dérivé ;

Mots-clés espagnols / Spanish Keywords

Duelo ; Muerte ; Cónyuge ; Compañero sexual ; Angustia ansiedad ; Tratamiento ; Diazepam ; Dosis débil ; Tranquilizante ; Psicotropo ; Quimioterapia ; Eficacia tratamiento ; Toxicidad ; Estudio longitudinal ; Hombre ; Benzodiazepina derivado ;

Localisation / Location

INIST-CNRS, Cote INIST : 3999, 35400009396111.0080