Titre du document / Document title

A decline in the pulmonary diffusing capacity does not indicate opportunistic lung disease in asymptomatic persons infected with the human immunodeficiency virus

Auteur(s) / Author(s)

KVALE P. A. ; ROSEN M. J. ; HOPEWELL P. C. ; MARKOWITZ N. ; HANSEN N. ; REICHMAN L. B. ; WALLACE J. M. ; GLASSROTH J. ; FULKERSON W. ; MEISELMAN L. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

National heart lung blood inst., div. lung disease, Detroit MI, ETATS-UNIS

Résumé / Abstract

We enrolled 1,353 subjects in a multicenter study to evaluate the spectrum of pulmonary complications associated with human immundeficiency virus (HIV) infection and the feasibility of detecting pulmonary infections in asymptomatic members of this group. There were 1,171 who were HIV-seropositive; the remaining 182 were HIV-seronegative, but they belonged to high-risk transmission groups (homosexual/bisexual, or injection drug users). Single-breath carbon monoxide diffusing capacity (DL_CO) was measured serially (at 3- to 12-month intervals) in a prospective fashion to determine whether a decline of ≥20% predicted the presence of Pneumocystis carinii pneumonia or other pulmonary infections in the absence of new pulmonary symptoms and no new abnormalities on chest roeentgenograms

Revue / Journal Title

The American review of respiratory disease   ISSN 0003-0805   CODEN ARDSBL 

Source / Source

1993, vol. 148, n^o2, pp. 390-395 (22 ref.)

Langue / Language

Anglais

Editeur / Publisher

American Lung Association, New York, NY, ETATS-UNIS  (1959-1993) (Revue)

Mots-clés anglais / English Keywords

Infection ; AIDS ; Lung ; Exploration ; Prognosis ; Human ; Lung function ; Breath test ; Seropositivity ; Human immunodeficiency virus ; Asymptomatic ; Respiratory disease ; Hemopathy ; Immunopathology ; Viral disease ; Lentivirinae ; Retroviridae ; Virus ;

Mots-clés français / French Keywords

Infection ; Immunodéficit acquis syndrome ; Poumon ; Exploration ; Pronostic ; Homme ; Fonction respiratoire ; Test respiratoire ; Séropositivité ; Virus immunodéficience humaine ; Asymptomatique ; Appareil respiratoire pathologie ; Hémopathie ; Immunopathologie ; Virose ; Lentivirinae ; Retroviridae ; Virus ;

Mots-clés espagnols / Spanish Keywords

Infección ; Inmunodeficiencia adquirida síndrome ; Pulmón ; Exploración ; Pronóstico ; Hombre ; Función respiratoria ; Test respiratorio ; Seropositividad ; Human immunodeficiency virus ; Asintomático ; Aparato respiratorio patología ; Hemopatía ; Inmunopatología ; Virosis ; Lentivirinae ; Retroviridae ; Virus ;

Localisation / Location

INIST-CNRS, Cote INIST : 2013, 35400003553865.0190