Titre du document / Document title
0.3% ciprofloxacin ophthalmic ointment in the treatment of bacterial keratitis
Auteur(s) / Author(s)
WILEHLMUS K. R.
(1) ;
HYNDIUK R. A. ;
CALDWELL D. R. ;
ABSHIRE R. L. ;
FOLKENS A. T. ;
GODIO L. B. ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Baylor coll. medicine, cullen eye inst., Houston TX, ETATS-UNIS
Résumé / Abstract
Objective: To determine the efficacy and safety of topical 0.3% ciprofloxacin hydrochloride ophthalmic ointment in the treatment of bacterial keratitis. Design: Prospective case series with a nonrandomized comparison of culture-positive, evaluable cases (ciprofloxacin ointment group) with culture-positive, concurrent patients (nonenrolled group) treated with conventional therapy. Setting: Multicenter clinical study. Patients: After informed consent was obtained, 253 eligible patients underwent corneal scrapings and received topical ciprofloxacin ointment; 145 (57%) had positive cultures and completed the follow-up schedule. Forty (70%) of 57 apparently eligible patients had culture-positive bacterial keratitis but were not enrolled in the ciprofloxacin ointment study during the same period
Revue / Journal Title
Archives of ophthalmology
ISSN 0003-9950
Source / Source
1993, vol. 111, n
o9, pp. 1210-1218 (17 ref.)
Langue / Language
Anglais
Editeur / Publisher
American Medical Association, Chicago, IL, ETATS-UNIS
(1960)
(Revue)
Mots-clés anglais / English Keywords
Keratitis ;
Chemotherapy ;
Treatment ;
Antibacterial agent ;
Statistical study ;
Human ;
Antibiotic ;
Ointment ;
Ophthalmic preparation ;
Treatment efficiency ;
Fluoroquinolone derivative ;
Bacteriosis ;
Infection ;
Eye disease ;
Keratopathy ;
Mots-clés français / French Keywords
Kératite ;
Chimiothérapie ;
Ciprofloxacine ;
Traitement ;
Antibactérien ;
Etude statistique ;
Homme ;
Antibiotique ;
Pommade ;
Forme ophtalmique ;
Efficacité traitement ;
Fluoroquinolone dérivé ;
Bactériose ;
Infection ;
Oeil pathologie ;
Kératopathie ;
Mots-clés espagnols / Spanish Keywords
Queratitis ;
Quimioterapia ;
Tratamiento ;
Antibacteriano ;
Estudio estadístico ;
Hombre ;
Antibiótico ;
Pomada ;
Forma oftálmica ;
Eficacia tratamiento ;
Bacteriosis ;
Infección ;
Ojo patología ;
Queratopatía ;
Localisation / Location
INIST-CNRS, Cote INIST : 2033, 35400004752938.0140
Nº notice refdoc (ud4) : 4881483
