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Titre du document / Document title

Evaluation of new occult blood tests for detection of colorectal neoplasia

Auteur(s) / Author(s)

ST JOHN D. J. B. (1) ; YOUNG G. P. ; ALEXEYEFF M. A. (1) ; DEACON M. C. ; CUTHBERTSON A. M. ; MACRAE F. A. (1) ; PENFOLD J. C. B. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Royal Melbourne hosp., dep. gastroenterology, Melbourne Victoria 3050, AUSTRALIE

Résumé / Abstract

Background: Hemoccult II, the guaiac-based fecal occult blood test used in most colorectal cancer screening programs, has an unsatisfactory sensitivity for asymptomatic colorectal neoplasms. We evaluated the relative performance of four fecal occult blood tests, directed against various components of the hemoglobin molecule. Methods: All tests, Hemoccult II, HemoccultSENSA (a more sensitive guaiac test), HemeSelect (an immunochemical test specific for human hemoglobin), and HemoQuant (the heme-porphyrin assay), were performed by 107 patients with symptomatic colorectal cancer and 81 patients with predominantly asymptomatic adenoma. HemoccultSENSA and HemeSelect were performed by 1,355 screenees

Revue / Journal Title

Gastroenterology   ISSN 0016-5085   CODEN GASTAB 

Source / Source

1993, vol. 104, no6, pp. 1661-1668 (53 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, New York, NY, ETATS-UNIS  (1943) (Revue)

Mots-clés anglais / English Keywords

Tumor ; Evaluation ; Colon ; Rectum ; Technique ; Diagnosis ; Blood ; Colonic disease ; Rectal disease ; Digestive diseases ; Feces ; Human ; Asymptomatic ;

Mots-clés français / French Keywords

Tumeur ; Evaluation ; Côlon ; Rectum ; Technique ; Diagnostic ; Hemoccult II ; Sang ; Côlon pathologie ; Rectum pathologie ; Appareil digestif pathologie ; Feces ; Homme ; Asymptomatique ;

Mots-clés espagnols / Spanish Keywords

Tumor ; Evaluación ; Colón ; Recto ; Técnica ; Diagnóstico ; Sangre ; Colón patología ; Recto patología ; Aparato digestivo patología ; Heces ; Hombre ; Asintomático ;

Localisation / Location

INIST-CNRS, Cote INIST : 2090, 35400003395895.0110

Nº notice refdoc (ud4) : 4775804

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