Titre du document / Document title
Immunohistopathologic features and therapy of conjunctival lichen planus
Auteur(s) / Author(s)
NEUMANN R. ;
DUTT C. J. ;
FOSTER C. S. ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
Harvard medical school, Massachusetts eye ear infirmary, immunology serv., Boston MA, ETATS-UNIS
Résumé / Abstract
Lichen planus is an autoimmune disease that typically involves skin and the mucosa of the genitalia and mouth. Conjunctival involvement is rare, and the microscopic abnormalities of affected conjunctivae are not well characterized. We treated two patients with cicatrizing conjunctivitis and extraocular conjunctival lichen planus confirmed by biopsy. We found irregular, thickened basement membrane with reduplications similar to the findings in oral mucosa affected by lichen planus. The absence of basement membrane immunoreactants excluded ocular cicatricial pemphigoid. Results of laboratory tests for collagen vascular diseases including sarcoidosis and lupus were also negative
Revue / Journal Title
American journal of ophthalmology
ISSN 0002-9394
CODEN AJOPAA
Source / Source
1993, vol. 115, n
o4, pp. 494-500 (21 ref.)
Langue / Language
Anglais
Editeur / Publisher
Elsevier, New York, NY, ETATS-UNIS
(1884)
(Revue)
Mots-clés anglais / English Keywords
Lichen planus ;
Conjunctiva ;
Immunohistochemistry ;
Chemotherapy ;
Pathology ;
Exploration ;
Treatment ;
Case study ;
Autoimmune disease ;
Eye disease ;
Immunosuppressive agent ;
Ophthalmic preparation ;
Differential diagnostic ;
Adult ;
Human ;
Conjonctiva disease ;
Mots-clés français / French Keywords
Lichen plan ;
Conjonctive ;
Immunohistochimie ;
Chimiothérapie ;
Anatomopathologie ;
Exploration ;
Traitement ;
Ciclosporine ;
Etude cas ;
Maladie autoimmune ;
Oeil pathologie ;
Immunodépresseur ;
Forme ophtalmique ;
Diagnostic différentiel ;
Adulte ;
Homme ;
Conjonctive pathologie ;
Mots-clés espagnols / Spanish Keywords
Liquen plano ;
Conjuntiva ;
Inmunohistoquímica ;
Quimioterapia ;
Anatomía patológica ;
Exploración ;
Tratamiento ;
Estudio caso ;
Enfermedad autoinmune ;
Ojo patología ;
Inmunodepresor ;
Forma oftálmica ;
Diagnóstico diferencial ;
Adulto ;
Hombre ;
Localisation / Location
INIST-CNRS, Cote INIST : 2012, 35400003612018.0100
Nº notice refdoc (ud4) : 4695874
