Titre du document / Document title
The effects of testosterone treatment on body composition and metabolism in middle-aged obese men
Auteur(s) / Author(s)
MÅRIN P.
(1) ;
HOLMÄNG S. ;
JÖNSSON L. ;
SJÖSTRÖM L.
(1) ;
KVIST H. ;
HOLM G.
(1) ;
LINDSTEDT G. ;
BJÖRNTORP P.
(1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Univ. Göteborg, Sahlgren's hosp., dep. medicine I, 413 45 Göteborg, SUEDE
Résumé / Abstract
Twenty-three middle-aged abdominally obese men were treated for eight months with testosterone or with placebo. Testosterone treatment was followed by a decrease of visceral fat mass, measured by computerized tomography, without a change in body mass, subcutaneous fat mass or lean body mass. Insulin resistance, measured by the euglycemic/hyperinsulinemic glucose clamp method, improved and blood glucose, diastolic blood pressure and serum cholesterol decreased with testosterone treatment. A small increase in prostate volume was noted, but serum prostate specific antigen concentrations were unchanged and no adverse functional side-effects were found
Revue / Journal Title
International journal of obesity
ISSN 0307-0565
CODEN IJOBDP
Source / Source
1992, vol. 16, n
o12, pp. 991-997 (24 ref.)
Langue / Language
Anglais
Editeur / Publisher
Nature Publishing, Basingstoke, ROYAUME-UNI
(1977)
(Revue)
Mots-clés anglais / English Keywords
Obesity ;
Human ;
Male ;
Testosterone ;
Androgen ;
Treatment ;
Activity metabolism relation ;
Biological monitoring ;
Mechanism of action ;
Sex steroid hormone ;
Chemotherapy ;
Adult ;
Biological activity ;
Nutritional status ;
nutritional dissorder ;
Mots-clés français / French Keywords
Obésité ;
Homme ;
Mâle ;
Testostérone ;
Androgène ;
Traitement ;
Relation métabolisme activité ;
Surveillance biologique ;
Mécanisme action ;
Hormone stéroïde sexuelle ;
Chimiothérapie ;
Adulte ;
Activité biologique ;
Etat nutritionnel ;
trouble nutrition ;
Mots-clés espagnols / Spanish Keywords
Obesidad ;
Hombre ;
Macho ;
Testosterona ;
Andrógeno ;
Tratamiento ;
Relación metabolismo actividad ;
Vigilancia biológica ;
Mecanismo acción ;
Hormona esteroide sexual ;
Quimioterapia ;
Adulto ;
Actividad biológica ;
Estado nutricional ;
Localisation / Location
INIST-CNRS, Cote INIST : 18243, 35400003262806.0070
Nº notice refdoc (ud4) : 4509788
