Titre du document / Document title

Treatment of genital HPV infection with carbon dioxide laser and systemic interferon alpha-2b

Auteur(s) / Author(s)

NIEMINEN P. ; AHO M. ; LEHTINEN M. ; VESTERINEN E. ; VAHERI A. ; PAAVONEN J. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

Univ. Helsinki, Ministry health social affairs, FINLANDE

Résumé / Abstract

Background and Objectives: Treatment of genital warts is problematic. Numerous treatment modalities are available, but response to any therapy often is unsatisfactory. Recently, studies have suggested that interferons would be effective in the treatment of some genital warts. Goal of this Study: To compare carbon dioxide laser with or without adjuvant subcutaneously administered interferon alpha-2b in the treatment of genital human papillomavirus infection. Study Design: One hundred randomized women with genital HPV infection were treated with carbon dioxide laser and adjuvant systemic interferon alpha-2b or carbon dioxide laser and placebo. Patients were followed colposcopically, cytologically, and by HPV DNA testing for 6 months

Revue / Journal Title

Sexually transmitted diseases   ISSN 0148-5717   CODEN STRDDM 

Source / Source

1994, vol. 21, n^o2, pp. 65-69 (23 ref.)

Langue / Language

Anglais

Editeur / Publisher

Lippincott, Hagerstown, MD, ETATS-UNIS  (1977) (Revue)

Mots-clés anglais / English Keywords

Condyloma acuminatum ; Adjuvant treatment ; Antiviral ; Carbon dioxide ; Laser ; Alpha interferon ; Chemotherapy ; Subcutaneous administration ; Treatment efficiency ; Human ; Female ; Double blind study ; Randomization ; Viral disease ; Infection ; Female genital diseases ; Sexually transmitted disease ; Cytokine ;

Mots-clés français / French Keywords

Condylome acuminé ; Traitement adjuvant ; Antiviral ; Carbone dioxyde ; Laser ; Interféron alpha ; Chimiothérapie ; Voie souscutanée ; Efficacité traitement ; Homme ; Femelle ; Etude double insu ; Randomisation ; Virose ; Infection ; Appareil génital femelle pathologie ; Maladie sexuellement transmissible ; Cytokine ;

Mots-clés espagnols / Spanish Keywords

Condiloma acuminado ; Tratamiento adyuvante ; Antiviral ; Carbono dióxido ; Laser ; Interferón alfa ; Quimioterapia ; Vía subcutánea ; Eficacia tratamiento ; Hombre ; Hembra ; Estudio doble ciego ; Aleatorización ; Virosis ; Infección ; Aparato genital hembra patología ; Enfermedad de transmisión sexual ; Citoquina ;

Localisation / Location

INIST-CNRS, Cote INIST : 18921, 35400004577152.0020