Titre du document / Document title

Effects of mild asymptomatic primary hyperparathyroidism on bone mass in women with and without estrogen replacement therapy

Auteur(s) / Author(s)

MCDERMOTT M. T. ; PERLOFF J. J. ; KIDD G. S. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

Fitzsimons Army medical cent., endocrinology serv., Aurora CO 80045-5001, ETATS-UNIS

Résumé / Abstract

Primary hyperparathyroidism (HPT) presents most commonly as a mild elevation of the serum calcium concentration in an asymptomatic individual. There are conflicting data regarding the effects of mild primary HPT on bone mass. This cross-sectional study was conducted to examine this question further and to determine whether estrogen replacement therapy (ERT) in postmenopausal women with primary HPT might be beneficial. We measured bone mass in 59 women with mild asymptomatic primary HPT, of whom 43 (HPT) had never taken and 16 (estrogen-replaced HPT) were currently taking ERT. We also studied 84 healthy normocalcemic women who were not on ERT (controls) and 45 who were on ERT (estrogen-replaced controls)

Revue / Journal Title

Journal of bone and mineral research   ISSN 0884-0431   CODEN JBMREJ 

Source / Source

1994, vol. 9, n^o4, pp. 509-514 (30 ref.)

Langue / Language

Anglais

Editeur / Publisher

American Society for Bone and Mineral Research, Duham, NC, ETATS-UNIS  (1986) (Revue)

Mots-clés anglais / English Keywords

Human ; Female ; Hyperparathyroidism ; Bone mass ; Postmenopause ; Estrogen ; Replacement therapy ; Chemotherapy ; Hormone ; Endocrinopathy ; Parathyroid diseases ;

Mots-clés français / French Keywords

Homme ; Femelle ; Hyperparathyroïdie ; Masse osseuse ; Postménopause ; Oestrogène ; Traitement substitutif ; Chimiothérapie ; Hormone ; Endocrinopathie ; Parathyroïde pathologie ;

Mots-clés espagnols / Spanish Keywords

Hombre ; Hembra ; Hiperparatiroidismo ; Masa oseosa ; Postmenopausia ; Estrógeno ; Tratamiento sustitutivo ; Quimioterapia ; Hormona ; Endocrinopatía ; Paratiroides patología ;

Localisation / Location

INIST-CNRS, Cote INIST : 21114, 35400004956521.0090