Titre du document / Document title

Fungemia and colonization with nystatin-resistant Candida rugosa in a burn unit

Auteur(s) / Author(s)

DUBE M. P. ; HESELTINE P. N. R. ; RINALDI M. G. ; EVANS S. ; ZAWACKI B. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

Univ. Southern California school medicine, dep. medicine, Los Angeles CA, ETATS-UNIS

Résumé / Abstract

Yeast isolates from burned patients were analyzed retrospectively for a 7-year period (19841991). Topical nystatin was used routinely in the burn wound dressings as antifungal therapy beginning in July 1986. Nystatin use was associated with a significant decrease in overall yeast acquisitions in burn wounds; yeasts were isolated from 15.5% of admitted patients before the use ofnystatin vs. 10.5% with use of nystatin (odds ratio [OR]=0.64; 95% confidence interval [CI], 0.48-0.86). New acquisitions of Candida rugosa in burn wounds increased from 0.36% of admissions during the period July 1984 to June 1986 (before nystatin use) to 5.25% in the period July 1986 to June 1991 (during use of nystatin) (OR=15.3; 95% CI, 4.1-128)

Revue / Journal Title

Clinical infectious diseases   ISSN 1058-4838   CODEN CIDIEL 

Source / Source

1994, vol. 18, n^o1, pp. 77-82 (27 ref.)

Langue / Language

Anglais

Editeur / Publisher

University of Chicago Press, Chicago, IL, ETATS-UNIS  (1992) (Revue)

Mots-clés anglais / English Keywords

Burn ; Intensive care unit ; Candida rugosa ; Fungemia ; Nystatin ; Resistance ; Antifungal agent ; Wound ; Drug susceptibility test ; Minimum inhibitory concentration ; Human ; Fungi Imperfecti ; Fungi ; Thallophyta ; Mycosis ; Infection ; Resuscitation ;

Mots-clés français / French Keywords

Brûlure ; Unité soin intensif ; Candida rugosa ; Fongémie ; Nystatine ; Résistance ; Antifongique ; Plaie ; Test sensibilité médicamenteuse ; Concentration minimale inhibitrice ; Homme ; Infection nosocomiale ; Fungi Imperfecti ; Fungi ; Thallophyta ; Mycose ; Infection ; Réanimation ;

Mots-clés espagnols / Spanish Keywords

Quemadura ; Unidad terapia intensiva ; Candida rugosa ; Funguemia ; Resistencia ; Antifúngico ; Herida ; Prueba sensibilidad medicamentosa ; Concentración mínima inhibidora ; Hombre ; Fungi Imperfecti ; Fungi ; Thallophyta ; Micosis ; Infección ; Reanimación ;

Localisation / Location

INIST-CNRS, Cote INIST : 18407, 35400002492412.0070