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Titre du document / Document title

Milk transfer and tissue uptake of mercury in suckling offspring after exposure of lactating maternal guinea pigs to inorganic or methylmercury

Auteur(s) / Author(s)

YOSHIDA M. (1) ; WATANABE C. ; SATOH H. ; KISHIMOTO T. (1) ; YAMAMURA Y. (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) St. Marianna univ. school medicine, dep. public health, Miyamae-ku, Kawasaki 216, JAPON

Résumé / Abstract

Maternal guinea pigs were injected with mercuric chloride (HgCl2; 1 mg Hg/kg body weight) or methylmercury (MeHg; 1 mg Hg/kg) 12 h after parturition, and exposure of the offspring to mercury (Hg) via breast milk were studied on days 3, 5 and 10 postpartum. Milk Hg concentrations were lower than maternal plasma Hg concentrations regardless of the form of Hg given to the dams. Milk Hg was higher in HgCl2-treated dams than in MeHg-treated dams. In MeHg-treated dams, MeHg was separately determined. While the ratio of MeHg to T-Hg decreased in the dams'plasma, it did not in the milk. There was a strong correlation between milk and plasma T-Hg concentrations in HgCl2 treated dams

Revue / Journal Title

Archives of toxicology    ISSN  0340-5761   CODEN ARTODN 

Source / Source

1994, vol. 68, no3, pp. 174-178 (16 ref.)

Langue / Language

Anglais

Editeur / Publisher

Springer, Heidelberg, ALLEMAGNE  (1974) (Revue)

Mots-clés anglais / English Keywords

Mercury

;

Heavy metal

;

Guinea pig

;

Animal

;

Milk transfer

;

Comparative study

;

Rodentia

;

Mammalia

;

Vertebrata

;

Mots-clés français / French Keywords

Mercure

;

Métal lourd

;

Cobaye

;

Animal

;

Passage lait

;

Etude comparative

;

Mercure II?Chlorure

;

Mercure(méthyl)

;

Rodentia

;

Mammalia

;

Vertebrata

;

Mots-clés espagnols / Spanish Keywords

Mercurio

;

Metal pesado

;

Cobayo

;

Animal

;

Paso leche

;

Estudio comparativo

;

Rodentia

;

Mammalia

;

Vertebrata

;

Localisation / Location

INIST-CNRS, Cote INIST : 7527, 35400004945193.0040

Nº notice refdoc (ud4) : 3969242



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