Titre du document / Document title

Herbs of the genus Phyllanthus in the treatment of chronic hepatitis B : observations with three preparations from different geographic sites

Auteur(s) / Author(s)

WANG MEIXIA ; CHENG HAOWEI ; LI YANJUN ; MENG LINMIN ; ZHAO GUOLONG ; MAI KAI ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

Henan medical univ., Henan inst. medical sci., Henan 450052, CHINE

Résumé / Abstract

It has been suggested that herbs of the Phyllanthus family may have antiviral activity. We therefore tested the effects of three different Phyllanthus extracts on the serologic status of 123 patients with chronic hepatitis B. Eleven patients received an extract of Phyllanthus amarus (L) provided by S.P. Thyagarajan, Madras, India. Forty-two patients received Phyllanthus niruri (L), gathered from Hainan Province in China, and 35 patients received an extract of Phyllanthus urinaria (L), which had been gathered in Henan Province. Thirty-five control patients received no herbal therapy. The patients receiving Phyllanthus urinaria (L) were both more likely to lose detectable hepatitis B e-antigen from their serum and more likely to seroconvert hepatitis B e-antibody status from negative to positive than were patients given either of the other two preparations. No patient changed status with respect to hepatitis B s-antigen.

Revue / Journal Title

The Journal of laboratory and clinical medicine   ISSN 0022-2143   CODEN JLCMAK 

Source / Source

1995, vol. 126, n^o4, pp. 350-352 (12 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, Saint Louis, MO, ETATS-UNIS  (1915-2006) (Revue)

Mots-clés anglais / English Keywords

Medicinal plant ; Euphorbiaceae ; Chronic ; Viral hepatitis B ; Treatment ; Chemotherapy ; Antiviral ; Plant origin ; Biological effect ; Serology ; Hepatitis B virus ; Hepatitis B surface antigen ; Hepatitis B e antigen ; Folk medicine ; Human ; Chinese medicine ; Dicotyledones ; Angiospermae ; Spermatophyta ; Viral disease ; Infection ; Hepadnaviridae ; Virus ; Digestive diseases ; Hepatic disease ;

Mots-clés français / French Keywords

Plante médicinale ; Euphorbiaceae ; Chronique ; Hépatite virale B ; Traitement ; Chimiothérapie ; Antiviral ; Origine végétale ; Effet biologique ; Sérologie ; Virus hépatite B ; Antigène HBs ; Antigène HBe ; Médecine traditionnelle ; Homme ; Phyllanthus amarus ; Phyllanthus urinaria ; Phyllanthus niruri ; Médecine chinoise ; Dicotyledones ; Angiospermae ; Spermatophyta ; Virose ; Infection ; Hepadnaviridae ; Virus ; Appareil digestif pathologie ; Foie pathologie ;

Mots-clés espagnols / Spanish Keywords

Planta medicinal ; Euphorbiaceae ; Crónico ; Hepatitis vírica B ; Tratamiento ; Quimioterapia ; Antiviral ; Origen vegetal ; Efecto biológico ; Serología ; Hepatitis B virus ; Antígeno HBs ; Antígeno HBe ; Medicina tradicional ; Hombre ; Dicotyledones ; Angiospermae ; Spermatophyta ; Virosis ; Infección ; Hepadnaviridae ; Virus ; Aparato digestivo patología ; Hígado patología ;

Localisation / Location

INIST-CNRS, Cote INIST : 2060, 35400005056487.0030