Titre du document / Document title

Lagophthalmos in a multibacillary population under multidrug therapy in the People's Republic of China

Auteur(s) / Author(s)

COURTRIGHT P. ⁽¹⁾ ; LEWALLEN S. ; LI H.-Y. ; HU L.-F. ; YANG J.-W. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Univ. Bristih Columbia, St Paul's hosp., dep. ophthalmology, Vancouver BC V6Z 1Y6, CANADA

Résumé / Abstract

Lagophthalmos may be the most common potentially blinding ocular condition in leprosy. The magnitude of the problem among multibacillary patients has not been determined. We sought to ascertain the magnitude of lagophthalmos in a multibacillary leprosy patient population under multidrug therapy (MDT) (both newly diagnosed and with a prior history of dapsone monotherapy) in China and assess factors associated with its presence. In a survey of 640 multibacillary patients 3.8% of the newly diagnosed patients and 10.2% of the patients with prior dapsone monotherapy had lagophthalmos. Corneal disease and vision loss were common in both groups. Poor compliance with MDT, duration between onset and diagnosis, and duration on dapsone monotherapy were associated with the presence of lagophthalmos. Our findings suggest that there may be a threshold at which MDT must be maintained to prevent lagophthalmos. Early leprosy diagnosis and treatment would also lessen the incidence of lagophthalmos in these patients. The high proportion of lagophthalmos patients with corneal disease suggests that there has been inadequate eye care for these patients.

Revue / Journal Title

Leprosy review   ISSN 0305-7518   CODEN LEREAA 

Source / Source

1995, vol. 66, n^o3, pp. 214-219 (10 ref.)

Langue / Language

Anglais

Editeur / Publisher

LEPRA, Colchester, ROYAUME-UNI  (1930) (Revue)

Mots-clés anglais / English Keywords

Leprosy ; Treatment ; Polychemotherapy ; Lagophthalmos ; Complication ; Association ; Human ; China ; Multibacillar leprosy ; Mycobacterial infection ; Bacteriosis ; Infection ; Asia ; Skin disease ; Eye disease ; Eyelid disease ;

Mots-clés français / French Keywords

Lèpre ; Traitement ; Polychimiothérapie ; Lagophtalmie ; Complication ; Association ; Homme ; Chine ; Lèpre multibacillaire ; Mycobactériose ; Bactériose ; Infection ; Asie ; Peau pathologie ; Oeil pathologie ; Paupière pathologie ;

Mots-clés espagnols / Spanish Keywords

Lepra ; Tratamiento ; Poliquimioterapia ; Lagoftalmía ; Complicación ; Asociación ; Hombre ; China ; Micobacteriosis ; Bacteriosis ; Infección ; Asia ; Piel patología ; Ojo patología ; Párpado patología ;

Localisation / Location

INIST-CNRS, Cote INIST : 4005, 35400005482253.0040