Titre du document / Document title
Microbiological and pharamcological studies on extracts of Cucurbita maxima
Auteur(s) / Author(s)
VILLASENOR I. M. ;
BARTOLOME A. L. O. ;
DACLAN L. C. ;
MANATAD A. J. G. ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
Univ. Philippines Diliman, inst. chemistry, Quezon City 1101, PHILIPPINES
Résumé / Abstract
Extracts from the fruits, leaves and flowers of Cucurbita maxima Duschne were subjected to preliminary microbiological and pharmacological studies. The undiluted ethanol extracts of squash fruits exhibited complete inhibition against B. subtilis and only partial inhibition against E. coli. The extracts of squash flowers and leaves showed either minimal or an absence of antimicrobial activity against both organisms. In the pharmacological screening of the crude extracts of squash fruits and leaves, there was a decrease in motor activity, ataxia, temporary palpebral ptosis, hyperaemia, micturition and abdominal gripping in the test mice. The ethyl acetate extract of squash flowers caused a decrease in respiratory rate, analgesia, paralysis of the hindlegs, persistent skin folds, hyperaemia, diarrhoea, and exophthalamos.
Revue / Journal Title
PTR. Phytotherapy research
ISSN
0951-418X
Source / Source
1995, vol. 9, n
o5, pp. 376-378 (14 ref.)
Langue / Language
Anglais
Editeur / Publisher
Wiley, Chichester, ROYAUME-UNI
(1987)
(Revue)
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Localisation / Location
INIST-CNRS, Cote INIST : 21695, 35400005373809.0130
Nº notice refdoc (ud4) : 3608140
