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Titre du document / Document title

Primary nocturnal enuresis : a comparison among observation, imipramine, desmopressin acetate and bed-wetting alarm systems

Auteur(s) / Author(s)


Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

Mayo clin., Rochester MO 55905, ETATS-UNIS

Résumé / Abstract

Patients with primary nocturnal enuresis were entered into 4 treatment groups : observation, imipramine, desmopressin acetate or alarm therapy. Patients were weaned from therapy 6 months after inclusion in the study and were evaluated for continence at 3, 6, 9 and 12 months after beginning the study protocol. Of the 50 patients under observation 6% were continent at 6 months and 16% were continent within 12 months. Of 44 patients treated with imipramine 36% were continent at 6 months on medication ; however, only 16% were continent at 12 months, off medication. Similarly, of the 88 patients treated with desmopressin acetate 68% were continent at 6 months but only 10% were continent at 12 months. Of the 79 patients treated with alarm therapy 63% were continent at 6 months and 56% were dry at 12 months. Although each form of therapy improved continence over observation alone (p <0.01), only the bed-wetting alarm system demonstrated persistent effectiveness (p <0.001).

Revue / Journal Title

The Journal of urology    ISSN  0022-5347   CODEN JOURAA 

Source / Source

American Academy of Pediatrics ; Section on Urology. Annual meeting, Dallas TX , ETATS-UNIS (22/10/1994)
1995, vol. 154 (2), no 2 (265 p.)  (26 ref.), pp. 745-748

Langue / Language


Editeur / Publisher

Elsevier, New York, NY, ETATS-UNIS  (1917) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 2081, 35400005194361.0200

Nº notice refdoc (ud4) : 3607435

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