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Titre du document / Document title

Effects of sodium bicarbonate, disodium carbonate, and a sodium bicarbonate/carbonate mixture on the Pco2 of blood in a closed system

Auteur(s) / Author(s)

SHAPIRO J. I. ; ELKINS N. ; LOGAN J. ; FERSTENBERG L. B. ; REPINE J. E. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

Univ. Colorado health sci. cent., Webb-Waring inst. biomedical res., dep. medicine and radiology, Denver CO, ETATS-UNIS

Résumé / Abstract

The effects of adding Carbicarb-a 50 :50 mixture of sodium bicarbonate (NaHCO3) and sodium carbonate (Na2CO3)-or sodium bicarbonate or disodium carbonate individually to whole blood were examined in vitro. Adding HCI to Mood in an open system rapidly decreased the pH and [HCO3-] without increasing partial pressure of carbon dioxide (PCO2), whereas adding HCI to blood in a closed system markedly decreased pH and increased PCO2. Adding sodium bicarbonate to blood caused a rapid and predictable increase in Pco2 that was linearly related to the pH of the blood at the time of addition. Adding disodium carbonate to blood caused a rapid and predictable fall In PCO2 that was linearly related to the initial Pco2 of the blood at the time of addition. Adding Carbicarb to blood caused relatively little change in Pco2 over a wide range of initial pH and Pco2 values. (J LAB CLIN MED 1995 ;126 :65-9)

Revue / Journal Title

The Journal of laboratory and clinical medicine    ISSN  0022-2143   CODEN JLCMAK 

Source / Source

1995, vol. 126, no1, pp. 65-69 (10 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, St. Louis, MO, ETATS-UNIS  (1915-2006) (Revue)

Mots-clés anglais / English Keywords

Metabolic acidosis

;

Human

;

Treatment

;

Resuscitation

;

Hydrogencarbonates

;

Sodium

;

Carbonates

;

Water electrolyte resuscitation

;

Treatment efficiency

;

Partial pressure

;

Carbon dioxide

;

Mots-clés français / French Keywords

Acidose métabolique

;

Homme

;

Traitement

;

Réanimation

;

Hydrogénocarbonate

;

Sodium

;

Carbonate

;

Réanimation hydroélectrolytique

;

Efficacité traitement

;

Pression partielle

;

Carbone dioxyde

;

Solution équimolaire

;

Mots-clés espagnols / Spanish Keywords

Acidosis metabólica

;

Hombre

;

Tratamiento

;

Reanimación

;

Hidrógenocarbonato

;

Sodio

;

Carbonato

;

Reanimación hidroelectrolítica

;

Eficacia tratamiento

;

Presión parcial

;

Carbono dióxido

;

Localisation / Location

INIST-CNRS, Cote INIST : 2060, 35400005180220.0080

Nº notice refdoc (ud4) : 3605816



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