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Titre du document / Document title

Miles run per week and high-density lipoprotein cholesterol levels in healthy, middle-aged men : a dose-response relationship

Auteur(s) / Author(s)

KOKKINOS P. F. (1) ; HOLLAND J. C. (3) ; PUNEET NARAYAN (1) ; COLLERAN J. A. (2) ; DOTSON C. O. (4) ; PAPADEMETRIOU V. (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Veterans affairs medical cent., cardiology div., Washington DC 20422, ETATS-UNIS
(2) Georgetown univ. medical cent., cardiology div., Washington DC, ETATS-UNIS
(3) National defense univ., health/fitness directorate, Washington DC, ETATS-UNIS
(4) Univ. Maryland, dep. kinesiology, College Park, ETATS-UNIS

Résumé / Abstract

Objective: To examine the association between miles run per week and high-density lipoprotein cholesterol levels in healthy middle-aged men. Background: Regular exercise increases levels of high-density lipoprotein cholesterol. However, the exercise requirements for such increases are not well defined. Methods: Healthy, nonsmoking men (n=2906; age, 43±4 years) completed a questionnaire on health habits and physical activities and a symptom-limited exercise test. They were then stratified on the basis of the number of miles run per week. Six groups, with mileages of 0, 5, 9, 12, 17, and 31 per week, were established. Results: A gradual increase in high-densitylipoprotein cholesterol level was observed with increased miles (0.008-mmol/L [0.308-mg/dL] increase in high-density lipoprotein cholesterol level per mile). Most of the changes were associated with distances of 7 to 14 miles per week. Levels of low-density lipoprotein cholesterol, triglycerides, and the ratio of total cholesterol to high-density lipoprotein cholesterol also improved with weekly mileage. The high-density lipoprotein cholesterol level correlated significantly with all exercise components, anthropometric measures, and alcohol consumption. Group comparisons disclosed significant differences (P<.05) in exercise time to exhaustion, miles run per week, body fat, body weight, and body mass index. Age and alcohol consumption were similar across groups. Conclusions: These results indicate a dose-response relationship between miles run per week, high-density lipoprotein cholesterol level, and other lipoprotein-lipid levels. Most changes were noted in those who ran 7 to 14 miles per week at mild to moderate intensities. A mileage threshold for changes in high-density lipoprotein cholesterol level was not observed. However, when compared with those of the nonexercising group, high-density lipoprotein cholesterol levels attained statistical significance at 7 or more miles per week

Revue / Journal Title

Archives of internal medicine    ISSN  0003-9926   CODEN AIMDAP 

Source / Source

1995, vol. 155, no4, pp. 415-420 (36 ref.)

Langue / Language

Anglais

Editeur / Publisher

American Medical Association, Chicago, IL, ETATS-UNIS  (1960-2012) (Revue)

Mots-clés anglais / English Keywords

Physical exercise

;

Cholesterol HDL

;

Correlation analysis

;

Human

;

Male

;

Middle age

;

Mots-clés français / French Keywords

Exercice physique

;

Cholestérol HDL

;

Analyse corrélation

;

Homme

;

Mâle

;

Age mûr

;

Mots-clés espagnols / Spanish Keywords

Ejercicio físico

;

Colesterol HDL

;

Análisis correlación

;

Hombre

;

Macho

;

Edad media

;

Localisation / Location

INIST-CNRS, Cote INIST : 2040, 35400005665485.0090

Nº notice refdoc (ud4) : 3498824



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