Titre du document / Document title

The effect of L-carnitine, administered through intravenous infusion of glucose, on both glucose and insulin levels in healthy subjects

Auteur(s) / Author(s)

NEGRO P. ; GOSSETTI F. ; LA PINTA M. ; MARIANI P. ; CARBONI M. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

Univ. La Sapienza, inst. clin. surgery, div. gen. surgery, 00155 Rome, ITALIE

Résumé / Abstract

The goal of the present study was to evaluate the effect of L-carnitine on plasma glucose and insulin levels. Two parallel studies were set-up, of 40 and 20 healthy volunteers, respectively. Each group received 500 cc of 10% glucose or 5% glucose, to which were randomly added 4 g or 2 g of L-carnitine and administered a week apart. Results showed that L-carnitine was able to reduce the increase in glucose plasma levels induced by infusion of the glucose solution. This finding was not dependent on an insulin-dependent mechanism

Revue / Journal Title

Drugs under experimental and clinical research   ISSN 0378-6501   CODEN DECRDP 

Source / Source

1994, vol. 20, n^o6, pp. 257-262 (12 ref.)

Langue / Language

Anglais

Editeur / Publisher

Bioscience Ediprint, Geneva, SUISSE  (1977) (Revue)

Mots-clés anglais / English Keywords

Insulin ; Intravenous administration ; Normal ; Human ; Glucose ;

Mots-clés français / French Keywords

Insuline ; Lévocarnitine ; Voie intraveineuse ; Normal ; Homme ; Glucose ;

Mots-clés espagnols / Spanish Keywords

Insulina ; Vía intravenosa ; Normal ; Hombre ; Glucosa ;

Localisation / Location

INIST-CNRS, Cote INIST : 17208, 35400005824686.0060