Titre du document / Document title

Aicardi syndrome : natural history and possible predictors of severity

Auteur(s) / Author(s)

MENEZES A. V. ⁽¹⁾ ; MACGREGOR D. L. ; BUNCIC J. R. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Hosp. sick children, dep. ophthalmology, Toronto ON M5G 1X8, CANADA

Résumé / Abstract

Aicardi syndrome is defined by the clinical triad of infantile spasms, agenesis of the corpus callosum, and pathognomonic chorioretinal lacunae. Almost all patients are girls with severe cognitive and physical handicaps, and epilepsy. Fourteen patients with Aircardi syndrome, seen at The Hospital for Sick Children, Toronto, Ontario, Canada, between 1975 and 1992, were reviewed to document the natural history of the disease and obtain life-table estimates of survival. The relationship between 28 neurologic features present in infancy and clinical outcome, as measured by mobilility and cognitive function also was examined

Revue / Journal Title

Pediatric neurology   ISSN 0887-8994 

Source / Source

1994, vol. 11, n^o4, pp. 313-318 (13 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, New York, NY, ETATS-UNIS  (1985) (Revue)

Mots-clés anglais / English Keywords

Aicardi syndrome ; Case study ; Evolution ; Child ; Human ; Nervous system diseases ; Central nervous system disease ; Cerebral disorder ; Eye disease ; Congenital disease ; Malformation ;

Mots-clés français / French Keywords

Encéphalopathie infantile chronique Aicardi ; Etude cas ; Evolution ; Enfant ; Homme ; Système nerveux pathologie ; Système nerveux central pathologie ; Encéphale pathologie ; Oeil pathologie ; Maladie congénitale ; Malformation ;

Mots-clés espagnols / Spanish Keywords

Parálisis cerebral infantil crónica Aicardi ; Estudio caso ; Evolución ; Niño ; Hombre ; Sistema nervioso patología ; Sistema nervosio central patología ; Encéfalo patología ; Ojo patología ; Enfermedad congénita ; Malformación ;

Localisation / Location

INIST-CNRS, Cote INIST : 22170, 35400005797825.0080