Titre du document / Document title
Pretrolatum is not comedogenic in rabbits or humans : A critical reappraisal of the rabbit ear assay and the concept of acne cosmetica
Auteur(s) / Author(s)
KLIGMAN A. M. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, ETATS-UNIS
Résumé / Abstract
The objective was to find out whether petrolatum, previously reported to be comedogenic in the rabbit ear model, would worsen acne. Vaseline petrolatum jelly (Vaseline®, Chesebrough-Ponds) and Vaseline petrolatum jelly cream (Creamy Vaseline®, Chesebrough-Ponds) were applied to separate groups of ten acne patients each twice daily for eight weeks. No evidence of comedogenic potential was found by the follicular biopsy technique. Papulo-pustules significantly decreased in both groups. Greasiness cannot be equated with comedogenicity. The admonition for acne patients to seek oil-free skin care products has no scientific merit with regard ro comedogenicity. Cosmetics are an unlikely cause of the relatively high prevalence of post-adolescent female acne.
Revue / Journal Title
Journal of the Society of Cosmetic Chemists
ISSN
0037-9832
CODEN JSCCA5
Source / Source
1996, vol. 47, n
o1, pp. 41-48 (20 ref.)
Langue / Language
Anglais
Editeur / Publisher
Society of Cosmetic Chemists, New York, NY, ETATS-UNIS
(1947-1997)
(Revue)
Mots-clés anglais / English Keywords
Test method ;
Evaluation ;
Efficiency ;
Acne ;
Comedo ;
Dermatology ;
Raw materials ;
Petrolatum ;
Cosmetic ;
Formulation ;
Human ;
Skin disease ;
Mots-clés français / French Keywords
Méthode essai ;
Evaluation ;
Efficacité ;
Acné ;
Comédon ;
Dermatologie ;
Matière première ;
Petrolatum ;
Cosmétique ;
Formulation ;
Homme ;
Peau pathologie ;
Mots-clés espagnols / Spanish Keywords
Método ensayo ;
Evaluación ;
Eficacia ;
Acné ;
Comedón ;
Dermatología ;
Materia prima ;
Petrolato ;
Cosmético ;
Formulación ;
Hombre ;
Piel patología ;
Localisation / Location
INIST-CNRS, Cote INIST : 6978, 35400004382330.0040
Nº notice refdoc (ud4) : 3097361
