Titre du document / Document title

The lanolin paradox

Auteur(s) / Author(s)

WOLF R. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Maccabee Dermatologic Outpatient Clinic and the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, ISRAEL

Résumé / Abstract

Several puzzling aspects of the use of lanolin are discussed as 'lanolin paradoxes', in analogy with the 'paraben paradoxes'. Lanolin in topical therapeutic agents sensitizes a high proportion of patients, whereas the same lanolin is 'safe' in cosmetics so widely used by millions of individuals. Patients with an allergic contact dermatitis to lanolin in a medication applied to a stasis ulcer can nevertheless use lanolin-containing cosmetics and not experience a reaction. Lanolin-sensitive individuals often show false-negative patch test reactions to unaltered lanolin. Patch testing with 30% wool wax alcohols used in the standard patch test tray cannot be considered a reliable method for detecting and confirming lanolin allergies. There are too many false-positive and false-negative results using the standard patch test tray.

Revue / Journal Title

Dermatology   ISSN 1018-8665 

Source / Source

1996, vol. 192, n^o3, pp. 198-202 (44 ref.)

Langue / Language

Anglais

Editeur / Publisher

Karger, Basel, SUISSE  (1992) (Revue)

Mots-clés anglais / English Keywords

Lanolin ; Vehicle(excipient) ; Drug ; Cosmetic ; Skin test ; Patch ; Contact dermatitis ; False positive ; False negative ; Review ; Human ; Skin disease ; Allergy ; Immunopathology ;

Mots-clés français / French Keywords

Lanoline ; Excipient ; Médicament ; Cosmétique ; Test cutané ; Patch ; Dermatite contact ; Faux positif ; Faux négatif ; Article synthèse ; Homme ; Peau pathologie ; Allergie ; Immunopathologie ;

Mots-clés espagnols / Spanish Keywords

Lanolina ; Excipiente(vehiculo) ; Medicamento ; Cosmético ; Prueba cutáneo ; Parche ; Dermatitis de contacto ; Falso positivo ; Negativo falso ; Artículo síntesis ; Hombre ; Piel patología ; Alergia ; Inmunopatología ;

Localisation / Location

INIST-CNRS, Cote INIST : 4530, 35400004303906.0020