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Titre du document / Document title

The lanolin paradox

Auteur(s) / Author(s)

WOLF R. (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Maccabee Dermatologic Outpatient Clinic and the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, ISRAEL

Résumé / Abstract

Several puzzling aspects of the use of lanolin are discussed as 'lanolin paradoxes', in analogy with the 'paraben paradoxes'. Lanolin in topical therapeutic agents sensitizes a high proportion of patients, whereas the same lanolin is 'safe' in cosmetics so widely used by millions of individuals. Patients with an allergic contact dermatitis to lanolin in a medication applied to a stasis ulcer can nevertheless use lanolin-containing cosmetics and not experience a reaction. Lanolin-sensitive individuals often show false-negative patch test reactions to unaltered lanolin. Patch testing with 30% wool wax alcohols used in the standard patch test tray cannot be considered a reliable method for detecting and confirming lanolin allergies. There are too many false-positive and false-negative results using the standard patch test tray.

Revue / Journal Title

Dermatology    ISSN  1018-8665 

Source / Source

1996, vol. 192, no3, pp. 198-202 (44 ref.)

Langue / Language

Anglais

Editeur / Publisher

Karger, Basel, SUISSE  (1992) (Revue)

Mots-clés anglais / English Keywords

Lanolin

;

Vehicle(excipient)

;

Drug

;

Cosmetic

;

Skin test

;

Patch

;

Contact dermatitis

;

False positive

;

False negative

;

Review

;

Human

;

Skin disease

;

Allergy

;

Immunopathology

;

Mots-clés français / French Keywords

Lanoline

;

Excipient

;

Médicament

;

Cosmétique

;

Test cutané

;

Patch

;

Dermatite contact

;

Faux positif

;

Faux négatif

;

Article synthèse

;

Homme

;

Peau pathologie

;

Allergie

;

Immunopathologie

;

Mots-clés espagnols / Spanish Keywords

Lanolina

;

Excipiente(vehiculo)

;

Medicamento

;

Cosmético

;

Prueba cutáneo

;

Parche

;

Dermatitis de contacto

;

Falso positivo

;

Negativo falso

;

Artículo síntesis

;

Hombre

;

Piel patología

;

Alergia

;

Inmunopatología

;

Localisation / Location

INIST-CNRS, Cote INIST : 4530, 35400004303906.0020

Nº notice refdoc (ud4) : 3060563



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