Titre du document / Document title
Skeletal muscle GLUT-4 and postexercise muscle glycogen storage in humans
Auteur(s) / Author(s)
MCCOY M. (1) ;
PROIETTO J. (1) ;
HARGREAVES M. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Department of Physiology and Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria 3052, AUSTRALIE
Résumé / Abstract
The purpose of this study was to examine the relationship between skeletal muscle GLUT-4 protein and postexercise glycogen storage in human subjects fed adequate carbohydrate. Eleven men completed 2 h of cycling, and a biopsy of the vastus lateralis was performed immediately after exercise cessation for the determination of muscle GLUT-4 protein and glycogen concentrations, glycogen synthase activity, and citrate synthase activity. The subjects ingested meals providing 2.0 g carbohydrate/kg body weight at 0, 2, and 4 h postexercise, and a second biopsy was performed 6 h postexercise. Muscle glycogen concentration increased significantly during the 6-h recovery period (glycogen immediately postexercise, 27.2 ± 5.4 mmol/kg wet weight ; glycogen storage, 52.4 ± 2.9 mmol.kg wet weight
-1.6 h
-1 ; P < 0.05). Glycogen storage during recovery was directly related to GLUT-4 protein (2.20 ± 0.33 arbitrary standard units ; r = 0.63 ; P < 0.05) and inversely related to glycogen immediately postexercise (r = -0.70 ; P < 0.05). A direct correlation existed between glycogen storage during recovery and the activity of the I form of glycogen synthase (r = 0.60 ; P < 0.05). These results suggest that muscle GLUT-4 protein concentration, as well as factors relating to glucose disposal, may affect postexercise glycogen storage in humans fed adequate carbohydrate.
Revue / Journal Title
Journal of applied physiology
ISSN
8750-7587
CODEN JAPHEV
Source / Source
1996, vol. 80, n
o2, pp. 411-415 (26 ref.)
Langue / Language
Anglais
Editeur / Publisher
American Physiological Society, Bethesda, MD, ETATS-UNIS
(1985)
(Revue)
Mots-clés anglais / English Keywords
Striated muscle ;
Glycogen ;
Metabolic storage ;
Carrier protein ;
Glucose ;
Recovery ;
Physical exercise ;
Human ;
Mots-clés français / French Keywords
Muscle strié ;
Glycogène ;
Réserve métabolique ;
Protéine transport ;
Glucose ;
Récupération ;
Exercice physique ;
GLUT 4 ;
Homme ;
Mots-clés espagnols / Spanish Keywords
Músculo estriado ;
Glicógeno ;
Reserva metabólica ;
Proteína transportador ;
Glucosa ;
Recuperación ;
Ejercicio físico ;
Hombre ;
Localisation / Location
INIST-CNRS, Cote INIST : 5400, 35400005319406.0050
Nº notice refdoc (ud4) : 3033952
