RefDoc
Haut

Faire une nouvelle recherche
Make a new search
Lancer la recherche


Titre du document / Document title

Disappearance of Ewing's sarcoma following bacterial infection : A case report

Auteur(s) / Author(s)

MORI Y. (1) ; TSUCHIYA H. (1) ; TSUCHIDA T. (1) ; ASADA N. (1) ; NOJIMA T. (2) ; TOMITA K. (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Department of Orthopaedic Surgery, School of Medicine, Kanazawa University, 13-1, Takaramachi, Kanazawa, Ishikawa 920, ETATS-UNIS
(2) Department of Pathology, Kanazawa Medical University, 1-1, Uchinadamachi, Kahoku, Ishikawa 920-02, JAPON

Résumé / Abstract

We report a patient with multiple metastases of Ewing's sarcoma in whom the tumor vanished after a bacterial infection. To the best of our knowledge, no comparable case with Ewing's sarcoma has been reported in the literature. The patient was a 17-year-old male who had an irregular destructive lesion of the left pelvis on radiologic examination. Pathologic examination of a biopsy specimen revealed Ewing's sarcoma. After the operation, a roentgenogram showed multiple spinal metastases with paraplegia. Despite initiation of chemotherapy, a subsequent bone scan showed several areas of increased uptake indicating multiple metastatic lesions. A fistula with purulent discharge opened at the operative site. While being treated with antibiotics and fistula irrigation, the fistula narrowed and his high fever subsided. During this period, radiologic examinations indicated that the multiple bone metastases had nearly disappeared. Nine years after the operation, the patient is alive without any evidence of tumor. We postulate that the antitumor activity in this patient resulted from the bacterial infection, and believe that this case supports continued consideration of immunotherapy for cancer.

Revue / Journal Title

Anticancer research    ISSN  0250-7005 

Source / Source

1997, vol. 17, no2B, pp. 1391-1397 (16 ref.)

Langue / Language

Anglais

Editeur / Publisher

International Institute of Anticancer Research, Attiki, GRECE  (1980) (Revue)

Mots-clés anglais / English Keywords

Ewing sarcoma

;

Adolescent

;

Advanced stage

;

Metastasis

;

Bacteriosis

;

Pseudomonas aeruginosa

;

Staphylococcus epidermidis

;

Evolution

;

Survival

;

Long term

;

Case study

;

Bone

;

Chronic

;

Human

;

Infection

;

Pseudomonadaceae

;

Pseudomonadales

;

Bacteria

;

Micrococcaceae

;

Micrococcales

;

Diseases of the osteoarticular system

;

Malignant tumor

;

Mots-clés français / French Keywords

Réticulosarcome Ewing

;

Adolescent

;

Stade avancé

;

Métastase

;

Bactériose

;

Pseudomonas aeruginosa

;

Staphylococcus epidermidis

;

Evolution

;

Survie

;

Long terme

;

Etude cas

;

Os

;

Chronique

;

Homme

;

Infection

;

Pseudomonadaceae

;

Pseudomonadales

;

Bactérie

;

Micrococcaceae

;

Micrococcales

;

Système ostéoarticulaire pathologie

;

Tumeur maligne

;

Mots-clés espagnols / Spanish Keywords

Sarcoma Ewing

;

Adolescente

;

Estadio avanzado

;

Metástasis

;

Bacteriosis

;

Pseudomonas aeruginosa

;

Staphylococcus epidermidis

;

Evolución

;

Sobrevivencia

;

Largo plazo

;

Estudio caso

;

Hueso

;

Crónico

;

Hombre

;

Infección

;

Pseudomonadaceae

;

Pseudomonadales

;

Bacteria

;

Micrococcaceae

;

Micrococcales

;

Sistema osteoarticular patología

;

Tumor maligno

;

Localisation / Location

INIST-CNRS, Cote INIST : 19426, 35400006480009.0290

Nº notice refdoc (ud4) : 2640489



Faire une nouvelle recherche
Make a new search
Lancer la recherche
Bas