Titre du document / Document title

Lisinopril use in a large military medical center

Auteur(s) / Author(s)

WIREBAUGH S. R. ⁽¹⁾ ; SPENCER G. A. ⁽²⁾ ; MCINTYRE T. H. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Pharmacy, Wilford Hall Medical Center, Lackland Air Force Base, TX 78236-5300, ETATS-UNIS
⁽²⁾ Department of Internal Medicine, Wilford Hall Medical Center, Lackland Air Force Base, TX 78236-5300, ETATS-UNIS

Résumé / Abstract

The results of a drug use evaluation of lisinopril at a large teaching military medical center are reported. Indicators and thresholds were developed and approved by the Pharmacy and Therapeutics Committee. The medical charts of 227 patients for whom lisinopril was prescribed from June 1991 to June 1992 were reviewed for appropriateness of prescribing, appropriateness of monitoring, occurrence of any adverse drug reactions, and detection of drug interactions. Prescribing was appropriate in 97% and monitoring was appropriate in all reviewed cases. The most common adverse drug reactions detected were cough (7%), hypotension (3%), and rash (2%). Patients were also prescribed several drugs that may interact with lisinopril. Lisinopril appeared to be well tolerated and efficacious. Forty patients (18%) experienced adverse drug reactions related to lisinopril. There did not appear to be any major deficiencies with lisinopril prescribing and no corrective action needed to be taken other than educational activities for the appropriate use of lisinopril. Information from this drug use evaluation is useful in formulary decision making.

Revue / Journal Title

Military medicine   ISSN 0026-4075   CODEN MMEDA9 

Source / Source

1997, vol. 162, n^o2, pp. 113-117 (24 ref.)

Langue / Language

Anglais

Editeur / Publisher

Association of Military Surgeons, Bethesda, MD, ETATS-UNIS  (1955) (Revue)

Mots-clés anglais / English Keywords

Lisinopril ; ACE inhibitor ; Antihypertensive agent ; Chemotherapy ; Hypertension ; Heart failure ; Treatment ; Human ; Cardiovascular disease ; Heart disease ;

Mots-clés français / French Keywords

Lisinopril ; Inhibiteur angiotensin converting enzyme ; Antihypertenseur ; Chimiothérapie ; Hypertension artérielle ; Insuffisance cardiaque ; Traitement ; Homme ; Appareil circulatoire pathologie ; Cardiopathie ;

Mots-clés espagnols / Spanish Keywords

Lisinopril ; Inhibidor angiotensin converting enzyme ; Antihipertensivo ; Quimioterapia ; Hipertensión arterial ; Insuficiencia cardíaca ; Tratamiento ; Hombre ; Aparato circulatorio patología ; Cardiopatía ;

Localisation / Location

INIST-CNRS, Cote INIST : 2017, 35400006311238.0100