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Titre du document / Document title

Three-dimensional morphology and mechanics of bone scaffolds fabricated by rapid prototyping

Auteur(s) / Author(s)

JIN YU SIMON YOON (1) ; DEYHLE Hans (1) ; GBURECK Uwe (2) ; VORNDRAN Elke (2) ; BECKMANN Felix (3) ; MÜLLER Bert (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) University of Basel, Biomaterials Science Center, Basel, SUISSE
(2) University of Würzburg, Department for Functional Materials in Medicine and Dentistry, Würzburg, ALLEMAGNE
(3) Helmholtz-Zentrum Geesthacht, Institute of Materials Research, Geesthacht, ALLEMAGNE

Résumé / Abstract

Alpha-beta-tri-calcium phosphate is a promising biomaterial to fabricate scaffolds for the reconstruction of osseous defects. In the present study, we demonstrate that three-dimensional printing allows tailoring the porosity and the mechanical properties of nature-analogue designed scaffolds. Sophisticated software tools applied to the acquired tomography data were used to characterize the printing quality and the porosity by means of the distance transform, the radial density distribution and the accessibility by virtual spheres. Analyzing the stress―strain curves of the scaffolds, the Young's modulus and the ultimate compressive strength were obtained. To reach mechanical properties comparable to those of jaw bone, the scaffolds were treated with phosphoric acid. Depending on the design, the compressive strength of the bone scaffolds lies between 30 and 60 MPa and their Young's modulus is between 50 and 140 MPa. Hence, prototypes for clinical trials can be fabricated in near future.

Revue / Journal Title

International journal of materials research    ISSN  1862-5282 

Source / Source

2012, vol. 103, no 2 (116 p.)  [Document : 7 p.] (30 ref.), [Notes: This special issue is based on contributions to the "Tomographic 3D imaging with hard X-rays and neutrons" symposium of the EUROMAT2011 conference (European Congress and Exhibition on Avanced Materials and Processes).], pp. 200-206 [7 page(s) (article)]

Langue / Language

Anglais

Editeur / Publisher

Hanser, Munich, ALLEMAGNE  (2006) (Revue)

Mots-clés anglais / English Keywords

Mechanical properties

;

Young modulus

;

Elastic modulus

;

Elasticity

;

Calcium phosphate

;

Rapid prototyping

;

Morphology

;

Mots-clés français / French Keywords

Propriété mécanique

;

Module Young

;

Module élasticité

;

Elasticité

;

Phosphate de calcium

;

Prototypage rapide

;

Morphologie

;

Mots-clés espagnols / Spanish Keywords

Propiedad mecánica

;

Módulo Young

;

Módulo elasticidad

;

Elasticidad

;

Calcio fosfato

;

Prototipificación rápida

;

Morfología

;

Mots-clés d'auteur / Author Keywords

Tri-calcium phosphate

;

Bone scaffold

;

Micro computed tomography

;

3D morphology

;

Young's modulus

;

Localisation / Location

INIST-CNRS, Cote INIST : 271, 35400050678466.0100

Nº notice refdoc (ud4) : 25556958



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