Titre du document / Document title
Assessment of neuroendocrine dysfunction following traumatic brain injury
Auteur(s) / Author(s)
CHILDERS M. K. (1) ;
RUPRIGHT J. (1) ;
JONES P. S. (1) ;
MERVEILLE O. (2) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Department of Physical Medicine and Rehabilitation, University of Missouri-Columbia, Howard A. Rusk Rehabilitation Center, Columbia, Missouri, ETATS-UNIS
(2) Missouri Rehabilitation center, Mount Vernon, Missouri, ETATS-UNIS
Résumé / Abstract
Posttraumatic neuroendocrine pathology may be a clinically significant complication following traumatic brain injury (TBI). Metabolic abnormalities are described after TBI in two cases. A 21 year old male injured in a motor vehicle accident admitted in a minimally responsive condition presented with fluctuating high sodium levels, undetectable serum testosterone, and depressed cortisol and thyroid function. Imaging revealed near complete avulsion of the pituitary stalk leading to panhypotuitarism. A 38 year old male admitted for occipital skull fractures and brain contusions presented with hyponatremia and low serum testosterone. Both patients required hormonal replacement and correction of electrolyte abnormalities. A screening protocol adapted for selected patients at risk for endocrine problems is described. While neuroendocrine screening is not advocated in all TBI patients, physicians should be aware of the importance of neuroendocrine dysfunction following TBI.
Revue / Journal Title
Brain injury
ISSN
0269-9052
CODEN BRAIEO
Source / Source
1998, vol. 12, n
o6, pp. 517-523 (25 ref.)
Langue / Language
Anglais
Editeur / Publisher
Taylor & Francis, London, ROYAUME-UNI
(1987)
(Revue)
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Localisation / Location
INIST-CNRS, Cote INIST : 21327, 35400007659783.0070
Nº notice refdoc (ud4) : 2268991
