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Titre du document / Document title

Synthesis, Spectral, Thermal Analysis, Biological Activity and Kinetic Studies of Copper(II)-Pyridine-2,5-dicarboxylate Complexes with 2-Aminomethylpyridine and 8-Hydroxyquinoline

Auteur(s) / Author(s)

TOLGA COLAK Alper ; COLAK Ferdag ; ATAR Necip ; OLGUN Asim ;

Résumé / Abstract

In this work we report the synthesis of two novel square-planar copper(II) complexes, namely, (2-aminomethylpyridi-nium-pyridinedicarboxylato)copper(II) dihydrate, [Cu(pydc)(2-amp)] - 2H2O (1) and (8-hydroxyquinolinum-pyridine-dicarboxylato)copper(II) hydrate, [Cu(pydc)(8-HQ)] · H2O (2) (2-amp = 2-aminomethylpyridine, 8-HQ = 8-hydroxyquinoline, H2pydc = pyridine-2,5-dicarboxylic acid or isocinchomeronic acid) and present the first preliminary study on kinetics and biological activities of copper complexes. The synthesized complexes have been characterized by elemental, spectroscopic (FT-IR, UV and mass spectra), thermal analysis, magnetic and conductivity measurements techniques. Kinetic parameters were obtained for each stage of thermal degradation of the complexes using Coats-Redfern and Horowitz-Metzger methods. Antimicrobial activities of two complexes and two ligands were evaluated using agar diffusion method. Antimicrobial activity of complex 2 was determined with the agar dilution methods. The results were compared with two well known antibiotics, namely, tetracycline and nystatin.

Revue / Journal Title

Acta chimica slovenica    ISSN  1318-0207   CODEN ACSLE7 

Source / Source

2010, vol. 57, no1, pp. 212-221 [10 page(s) (article)]

Langue / Language

Anglais

Editeur / Publisher

Slovenian Chemical Society, Ljubljana, SLOVENIE  (1993) (Revue)

Mots-clés d'auteur / Author Keywords

Pyridine-2,5-dicarboxylato complexes

;

Copper(II) complexes

;

Antimicrobial activity

;

Thermal decomposition

;

Mass spectrometry

;

Localisation / Location

INIST-CNRS, Cote INIST : 16605, 35400018192386.0270

Nº notice refdoc (ud4) : 22593834



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