Titre du document / Document title

Mild-to-Moderate Symptoms during the First Year of Antiretroviral Therapy Worsen Quality of Life in HIV-Infected Individuals

Auteur(s) / Author(s)

Terry Beirn Community Programs for Clinical Research on AIDS, ETATS-UNIS
MANNHEIMER Sharon B. ^{(1 2)} ; WOLD Nicholas ⁽³⁾ ; GARDNER Edward M. ⁽⁴⁾ ; TELZAK Edward E. ^{(5 6 7)} ; HUPPLER HULLSIEK Katherine ⁽³⁾ ; CHESNEY Margaret ⁽⁸⁾ ; WU Albert W. ^{(9 10 11 12)} ; MACARTHUR Rodger D. ⁽¹³⁾ ; MATTS John ⁽³⁾ ; FRIEDLAND Gerald ⁽¹⁴⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Division of Infectious Diseases, Harlem Hospital Center, ETATS-UNIS
⁽²⁾ Department of Medicine, Columbia University College of Physicians and Surgeons, New York, ETATS-UNIS
⁽³⁾ Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, ETATS-UNIS
⁽⁴⁾ Division of Infectious Diseases, University of Colorado at Denver and Health Sciences Center, Denver, ETATS-UNIS
⁽⁵⁾ AIDS Program, Bronx-Lebanon Hospital Center, ETATS-UNIS
⁽⁶⁾ Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, ETATS-UNIS
⁽⁷⁾ Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, ETATS-UNIS
⁽⁸⁾ Division of Extramural Research and Training, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, ETATS-UNIS
⁽⁹⁾ Departments of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health and School of Medicine, Johns Hopkins University, Baltimore, Maryland, ETATS-UNIS
⁽¹⁰⁾ Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health and School of Medicine, Johns Hopkins University, Baltimore, Maryland, ETATS-UNIS
⁽¹¹⁾ Department of International Health, Johns Hopkins Bloomberg School of Public Health and School of Medicine, Johns Hopkins University, Baltimore, Maryland, ETATS-UNIS
⁽¹²⁾ Department of Medicine, Johns Hopkins Bloomberg School of Public Health and School of Medicine, Johns Hopkins University, Baltimore, Maryland, ETATS-UNIS
⁽¹³⁾ Division of Infectious Diseases, Wayne State University, Detroit, Michigan, ETATS-UNIS
⁽¹⁴⁾ AIDS Program, Yale School of Medicine, Yale New Haven Hospital, Yale University, New Haven, Connecticut, ETATS-UNIS

Résumé / Abstract

Symptoms and quality of life were assessed among human immunodeficiency virus (HIV)-infected individuals initiating their first course of antiretroviral therapy. Symptoms, which were mostly mild or moderate, were common in the first year and significantly affected the patients' quality of life. Quality of life was inversely related to the number of symptoms and in the change in the number of symptoms from baseline.

Revue / Journal Title

Clinical infectious diseases   ISSN 1058-4838   CODEN CIDIEL 

Source / Source

2008, vol. 46, n^o6, pp. 941-945 [5 page(s) (article)] (33 ref.)

Langue / Language

Anglais

Editeur / Publisher

University of Chicago Press, Chicago, IL, ETATS-UNIS  (1992) (Revue)

Mots-clés anglais / English Keywords

Immunopathology ; Immune deficiency ; Treatment ; Infection ; Viral disease ; Quality of life ; Antiretroviral agent ; Symptomatology ; Chemotherapy ; Antiviral ; AIDS ;

Mots-clés français / French Keywords

Immunopathologie ; Immunodéficit ; Traitement ; Infection ; Virose ; Qualité de vie ; Antirétroviral ; Symptomatologie ; Chimiothérapie ; Antiviral ; SIDA ;

Mots-clés espagnols / Spanish Keywords

Inmunopatología ; Inmunodeficiencia ; Tratamiento ; Infección ; Virosis ; Calidad vida ; Antiretroviral ; Sintomatología ; Quimioterapia ; Antiviral ; SIDA ;

Localisation / Location

INIST-CNRS, Cote INIST : 18407, 35400017362303.0220