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Titre du document / Document title

Peanut (Arachis hypogaea) Consumption Improves Glutathione and HDL-Cholesterol Levels in Experimental Diabetes

Auteur(s) / Author(s)

EMEKLI-ALTURFAN Ebru (1) ; KASIKCI Emel (1) ; YARAT Aysen (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Marmara University, Faculty of Dentistry, Department of Biochemistry, Nisantasi, Istanbul, TURQUIE

Résumé / Abstract

The aim of this investigation was to assess the influence of peanut (Arachis hypogaea) consumption on oxidant-antioxidant status and lipid profile in Streptozotocin (STZ) induced diabetic rats. 32 rats were divided into 4 groups as control, control+peanut, diabetic, diabetic+peanut. Control and diabetic groups were fed on standard rat chow whereas control+peanut and diabetic+peanut were fed on standard rat chow supplemented with 0.63 g % peanut for 12 weeks. Serum glucose levels, lipids, Glutathione (GSH), lipid peroxidation (LPO) and atherogenic index (AI) levels were determined at the end of the experiment. In the diabetic group TG (Triglyceride), TC (Total cholesterol), LDL-C (LDL-cholesterol) levels and atherogenic indexes increased significantly whereas HDL-C (HDL-cholesterol) level decreased significantly compared to the control group. The supplementation with peanut in the diabetic group led to significantly higher HDL-C levels and lower AI levels compared to diabetic group. Peanut consumption increased GSH levels significantly both in control and diabetic groups. In conclusion, this study shows that peanut consumption may improve oxidant-antioxidant status in healthy and diabetic status without increasing blood lipids. Moreover, increased HDL-C levels and decreased AI levels in diabetic rats indicate that, peanut consumption may have protective effects against cardiovascular complications of diabetes.

Revue / Journal Title

PTR. Phytotherapy research    ISSN  0951-418X 

Source / Source

2008, vol. 22, no2, pp. 180-184 [5 page(s) (article)] (1 p.)

Langue / Language

Anglais

Editeur / Publisher

Wiley, Chichester, ROYAUME-UNI  (1987) (Revue)

Mots-clés anglais / English Keywords

Endocrinopathy

;

Spermatophyta

;

Angiospermae

;

Dicotyledones

;

Leguminosae

;

Tripeptide

;

Sulfur peptide

;

Groundnut

;

Oil plant (vegetal)

;

Plant origin

;

Medicinal plant

;

Pharmacognosy

;

Lipids

;

Biological fluid

;

Serum

;

Antioxidant

;

Diabetes mellitus

;

Cholesterol HDL

;

Glutathione

;

Arachis hypogaea

;

Mots-clés français / French Keywords

Endocrinopathie

;

Spermatophyta

;

Angiospermae

;

Dicotyledones

;

Leguminosae

;

Tripeptide

;

Peptide soufre

;

Arachide

;

Plante oléagineuse

;

Origine végétale

;

Plante médicinale

;

Pharmacognosie

;

Lipide

;

Liquide biologique

;

Sérum

;

Antioxydant

;

Diabète

;

Cholestérol HDL

;

Glutathion

;

Arachis hypogaea

;

Mots-clés espagnols / Spanish Keywords

Endocrinopatía

;

Spermatophyta

;

Angiospermae

;

Dicotyledones

;

Leguminosae

;

Tripéptido

;

Péptido azufre

;

Aráquida

;

Planta oleaginosa

;

Origen vegetal

;

Planta medicinal

;

Farmacognosia

;

Lípido

;

Líquido biológico

;

Suero

;

Antioxidante

;

Diabetes

;

Colesterol HDL

;

Glutatión

;

Arachis hypogaea

;

Mots-clés d'auteur / Author Keywords

Peanut

;

diabetes

;

oxidant-antioxidant status

;

serum lipids

;

Localisation / Location

INIST-CNRS, Cote INIST : 21695, 35400017512691.0070

Nº notice refdoc (ud4) : 20126392



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