RefDoc
Haut

Faire une nouvelle recherche
Make a new search
Lancer la recherche


Titre du document / Document title

Role of nucleated red blood cell count in cases of birth asphyxia

Auteur(s) / Author(s)

MANZAR S. (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Division of Neonatology. Department of Child Health, Sultan Qaboos University Hospital, Al-Khoud, Muscat, OMAN

Résumé / Abstract

Objective: In spite of the improvement in the care of neonates in developing countries, birth asphyxia still remains a common problem. Asphyxia can occur antepartum, intrapartum or postpartum. Elevated nucleated red blood cell counts have been associated with in utero asphyxia in previous studies. Also nucleated red blood cell counts have been related to the timing of the asphyxia. This study was undertaken to look at the role of nucleated red blood cell count in asphyxiated neonates in relation to the outcome. Methods: In a retrospectively designed study all newborns with the diagnosis of asphyxia who were admitted to the neonatal intensive care unit at Sultan Qaboos University Hospital between November 1, 1995 to October 30, 1997 were reviewed. The medical charts were reviewed with respect to the parameters such as Apgar score, birth weight, sex, place of birth, value of nucleated red blood cell count at birth, duration of stay in hospital and mortality. A total of 27 term asphyxiated neonates were reviewed. Patients were divided into 2 groups depending upon their values of nucleated red blood cell count at birth. All patients with normal nucleated red blood cell counts (0.5-1.0 × 109/L or 3-10 per 100 WBC) were placed in group I and all with elevated nucleated red blood cell counts (> I × 109/L or >10 per 100 WBC) in group II, Results: Out of 27 neonates, 16 completed the study. Out of 16 neonates, 9 were placed in group 1 and the remaining 7 in group II. No significant difference was noted between the 2 groups with respect to the birth weight and severity of asphyxia. The neonates in group II, with elevated nucleated red blood cell counts, were noted to have increased mortality (28.5%) as compared to group I (11%). The neonates in group II also had prolonged hospital stay as compared to the neonates in group I, 8.7 ± 5.8 and 7.2±4.3 days. Conclusion: We concluded from the study that elevated nucleated red blood cell counts at birth in asphyxiated neonates, in addition to being used as a marker of fetal asphyxia and timing of asphyxia, may also be used as a prognostic marker in predicting the mortality and morbidity. However further prospective studies with larger population will be needed to confirm our findings.

Revue / Journal Title

Saudi medical journal    ISSN  0379-5284   CODEN SAMJDI 

Source / Source

1999, vol. 20, no9, pp. 703-705 (11 ref.)

Langue / Language

Anglais

Editeur / Publisher

Saudi Medical Journal, Riyadh, ARABIE SAOUDITE  (1979) (Revue)

Mots-clés anglais / English Keywords

Asphyxia

;

Newborn

;

Biological marker

;

Severity score

;

Fetus

;

Red blood cell

;

Assay

;

Evaluation

;

Oman

;

Human

;

Asia

;

Respiratory disease

;

Mots-clés français / French Keywords

Asphyxie

;

Nouveau né

;

Marqueur biologique

;

Indice gravité

;

Foetus

;

Erythrocyte

;

Dosage

;

Evaluation

;

Oman

;

Homme

;

Asie

;

Appareil respiratoire pathologie

;

Mots-clés espagnols / Spanish Keywords

Asfixia

;

Recién nacido

;

Marcador biológico

;

Indicio gravedad

;

Feto

;

Eritrocito

;

Dosificación

;

Evaluación

;

Omán

;

Hombre

;

Asia

;

Aparato respiratorio patología

;

Localisation / Location

INIST-CNRS, Cote INIST : 19973, 35400008918337.0090

Nº notice refdoc (ud4) : 1962411



Faire une nouvelle recherche
Make a new search
Lancer la recherche
Bas