Titre du document / Document title
Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and Thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats
Auteur(s) / Author(s)
MATSUDA H. (1) ;
SHIMODA H. (1) ;
YAMAHARA J. (1) ;
YOSHIKAWA M. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Kyoto Pharmaceutical University, 5 Nakauchi-cho, Misasagi, Yamashina-ku, Kyoto 607-8414, JAPON
Résumé / Abstract
We examined the antiallergic effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols A and F isolated from the processed leaves (Hydrangeae Dulcis Folium) and dried leaves of Hydrangea macrophylla SERINGE var. thunbergii MAKINO using the passive cutaneous anaphylaxis (PCA) reaction. With the exception of phyllodulcin, these constituents were found to significantly inhibit the PCA reaction. Although thunberginol A showed the most potent inhibitory effect, hydrangenol was considered to be the principal antiallergic component in the processed leaves, after taking into account their contents.
Revue / Journal Title
Biological & pharmaceutical bulletin
ISSN
0918-6158
Source / Source
1999, vol. 22, n
o8, pp. 870-872 (8 ref.)
Langue / Language
Anglais
Editeur / Publisher
Pharmaceutical Society of Japan, Tokyo, JAPON
(1993)
(Revue)
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Localisation / Location
INIST-CNRS, Cote INIST : 18096, 35400008973365.0190
Nº notice refdoc (ud4) : 1959604
