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Titre du document / Document title

Effect of Ixora coccinea flowers on dead space wound healing in rats

Auteur(s) / Author(s)

NAYAK B. S. (1) ; UDUPA A. L. (2) ; UDUPA S. L. (3) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Department of Clinical Biochemistry, Kasturba Medical College, Manipal Pin 576119, Kamataka, INDE
(2) Department of Pharmacology, Kasturba Medical College, Manipal Pin 576119, Kamataka, INDE
(3) Department of Biochemistry, Kasturba Medical College, Manipal Pin 576119, Karnataka, INDE

Résumé / Abstract

The alcoholic extract of the flowers of Ixora coccinea was studied for its effect on wound healing, using a dead space wound model in rats. Significant increases in granuloma tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content were observed. The prohealing actions seem to be due to increased collagen deposition as well as better alignment and maturation. The drug induced a hypertropic effect on the thymus gland but had no effect on the adrenals.

Revue / Journal Title

Fitoterapia    ISSN  0367-326X 

Source / Source

1999, vol. 70, no3, pp. 233-236 (14 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, Amsterdam, PAYS-BAS  (1934-1960) (Revue)

Mots-clés anglais / English Keywords

Plant origin

;

Flower

;

Biological activity

;

Healing agent

;

Wound

;

Extract

;

Rat

;

Animal

;

Pharmacognosy

;

Medicinal plant

;

Folk medicine

;

India

;

Rubiaceae

;

Dicotyledones

;

Angiospermae

;

Spermatophyta

;

Rodentia

;

Mammalia

;

Vertebrata

;

Asia

;

Mots-clés français / French Keywords

Origine végétale

;

Fleur

;

Activité biologique

;

Cicatrisant

;

Plaie

;

Extrait

;

Rat

;

Animal

;

Pharmacognosie

;

Plante médicinale

;

Médecine traditionnelle

;

Inde

;

Ixora coccinea

;

Rubiaceae

;

Dicotyledones

;

Angiospermae

;

Spermatophyta

;

Rodentia

;

Mammalia

;

Vertebrata

;

Asie

;

Mots-clés espagnols / Spanish Keywords

Origen vegetal

;

Flor

;

Actividad biológica

;

Cicatrizante

;

Herida

;

Extracto

;

Rata

;

Animal

;

Farmacognosia

;

Planta medicinal

;

Medicina tradicional

;

India

;

Rubiaceae

;

Dicotyledones

;

Angiospermae

;

Spermatophyta

;

Rodentia

;

Mammalia

;

Vertebrata

;

Asia

;

Localisation / Location

INIST-CNRS, Cote INIST : 16120, 35400008612575.0030

Nº notice refdoc (ud4) : 1918246



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