Titre du document / Document title
Determination of the etiological organism during acute exacerbations of COPD and efficacy of azithromycin, ampicillin-sulbactam, ciprofloxacin and cefaclor
Auteur(s) / Author(s)
UMUT S.
(1) ;
TUTLUOGLU B.
(1) ;
TOSUN G. A.
(1) ;
MÜSELLIM B.
(1) ;
ERK M.
(1) ;
YILDIRIM N.
(1) ;
VAHAPOGLU H.
(1) ;
YILMAZ N.
(1) ;
ARSEVEN O.
(1) ;
TÜRKER H.
(1) ;
ERELEL M.
(1) ;
ILVAN A.
(1) ;
GÖYLÜSÜN V.
(1) ;
KUYUCU T. Y.
(1) ;
KOSAR F.
(1) ;
SOYSAL F.
(1) ;
GÜR A.
(1) ;
UNUTMAZ S.
(1) ;
ÖZTÜRK S.
(1) ;
AKMAN M.
(1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Istanbul University Cerrahpasa School of Medicine, Dept. of Pulmonology, Istanbul, TURQUIE
Résumé / Abstract
Acute exacerbations, most of which are due to lower respiratory tract infections, cause great morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD) and most of these are due to lower respiratory tract infections. The aim of this study was to determine the causative organism and the effects of azithromycin, ampicillin sulbactam (sultamicillin), ciprofloxacin and cefaclor monohydrate therapy in COPD. One hundred and six patients with COPD in acute exacerbation were randomized into four groups for empiric antibiotic treatment following lung function tests and sputum examination. The most common strains isolated from sputum were Haemophilus influenzae (30.8%), Streptoccocus pneumoniae (12%) and Moraxella catarrhalis (7.7%). Azithromycin, sultamicillin, ciprofloxacin and cefaclor monohydrate were found to be effective in treating COPD exacerbations.
Revue / Journal Title
Journal of chemotherapy
ISSN 1120-009X
Source / Source
Congrès
National Congress of the Italian Society of Surgical Oncology (SICO) N
o22, Rome
, ITALIE
(09/1998)
1999, vol. 11, n
o 3, pp. 222-240 (12 ref.), pp. 211-214
Langue / Language
Anglais
Editeur / Publisher
EIFT, Firenze, ITALIE
(1989)
(Revue)
Mots-clés anglais / English Keywords
Obstructive pulmonary disease ;
Azithromycin ;
Sultamicillin ;
Ciprofloxacin ;
Cefaclor ;
Bacteriosis ;
Complication ;
Acute ;
Antibiotic ;
Antibacterial agent ;
Chemotherapy ;
Treatment ;
Human ;
Etiology ;
Bacteria ;
Macrolide ;
Penicillin derivatives ;
β-Lactams ;
Fluoroquinolone derivatives ;
Quinolone derivatives ;
Cephalosporin derivatives ;
Infection ;
Respiratory disease ;
Lung disease ;
Bronchus disease ;
Mots-clés français / French Keywords
Bronchopneumopathie obstructive ;
Azithromycine ;
Sultamicilline ;
Ciprofloxacine ;
Céfaclor ;
Bactériose ;
Complication ;
Aigu ;
Antibiotique ;
Antibactérien ;
Chimiothérapie ;
Traitement ;
Homme ;
Etiologie ;
Bactérie ;
Macrolide ;
Pénicilline dérivé ;
β-Lactamines ;
Fluoroquinolone dérivé ;
Quinolone dérivé ;
Céphalosporine dérivé ;
Infection ;
Appareil respiratoire pathologie ;
Poumon pathologie ;
Bronche pathologie ;
Mots-clés espagnols / Spanish Keywords
Broncopneumopatía obstructiva ;
Azitromicina ;
Sultamicilina ;
Ciprofloxacino ;
Cefaclor ;
Bacteriosis ;
Complicación ;
Agudo ;
Antibiótico ;
Antibacteriano ;
Quimioterapia ;
Tratamiento ;
Hombre ;
Etiología ;
Bacteria ;
Macrólido ;
Penicilinas ;
β-Lactams ;
Fluoroquinolone derivado ;
Quinolone derivado ;
Cefalosporina derivado ;
Infección ;
Aparato respiratorio patología ;
Pulmón patología ;
Bronquio patología ;
Localisation / Location
INIST-CNRS, Cote INIST : 20693, 35400008587033.0080
Nº notice refdoc (ud4) : 1899735
