Titre du document / Document title

Aclaramiento de creatinina y nefropatía por contraste en pacientes con creatinina normal = Creatinine clearance and contrast nephropathy in patients with normal creatinine levels

Auteur(s) / Author(s)

DE AGUSTIN Jose A. ; CARDA Rocio ; DEL Maria ; MANZANO C. ; RUIZ-MATEOS Borja ; GARCIA-RUBIRA Juan C. ; FERNANDEZ-ORTIZ Antonio ; VILACOSTA Isidre ; MACAYA Carlos ;

Résumé / Abstract

The main risk factor for contrast nephropathy is the presence of poor renal function. Plasma creatinine level is not a reliable measure of renal function as its value could lie within the normal range despite the presence of significant nephropathy. The purpose of this study was to evaluate the creatinine clearance rate as a predictor of contrast nephropathy in patients with a normal plasma creatinine level. The study included 273 consecutive patients with non-ST elevation acute coronary syndrome (NSTEACS) and a normal plasma creatinine level at admission who underwent coronary angiography. Patients who developed contrast nephropathy had a lower creatinine clearance rate at admission (66.3 mUmin vs. 83.4 mL/min; P<.001). A creatinine clearance rate < 80 mL/min had a sensitivity of 81% for predicting contrast nephropathy. Creatinine clearance should be measured routinely in patients with NSTEACS who are scheduled for coronary angiography.

Revue / Journal Title

Revista española de cardiología    ISSN  0300-8932 

Source / Source

2007, vol. 60, n^o7, pp. 772-776 [5 page(s) (article)]

Langue / Language

Espagnol

Editeur / Publisher

Elsevier, Barcelone, ESPAGNE  (1947) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 13819, 35400014668314.0100