Titre du document / Document title

Intersexualität beim Pferd = Intersexuality in horses

Auteur(s) / Author(s)

KUIPER H. ; DISTL O. ;

Résumé / Abstract

Intersexuality is a rare congenital anomaly of horses. Diagnosis of intersexuality is difficult because there are usually no specific changes in the reproductive tract visible. During a period of five years, ten patients with reduced fertility or suspected intersexuality respectively were investigated using cytogenetic, molecular genetic, histopathological and endocrinological methods. In one case a 64,XX/63,X0 mosaicism was found. In six cases male pseudohermaphroditism was verified. These patients showed a male karyotype, testes and rudimentary parts of a female reproductive tract were present. One horse was suspected to be a male pseudohermaphrodite but the gonads were not examined. One horse was suspected to be affected by an XX-sex several syndrome and in one case a SRY-negative XY-sex reversal syndrome was most likely. In the case of an XX-sex reversal syndrome, there is a female chromosomal constitution, an uterus and cranial parts of the vagina are present but also testes tissue and possibly an enlarged penis like clitoris. Here an XX-sex reversal syndrome was suspected but not confirmed as it was not possible to examine the gonads and verify tissue from testes. Therefore a pseudohermaphroditismus femininus could not be excluded. In cases of XY-sex reversal syndrome the patients show a male chromosomal constitution, parts of a female reproductive tract but no testes tissue is present. For the horse described here, a deletion of the SPY gene was the most likely cause for the XY-sex reversal syndrome.

Revue / Journal Title

DTW. Deutsche tierärztliche Wochenschrift   ISSN 0341-6593 

Source / Source

2007, vol. 114, n^o2, pp. 50-56 [7 page(s) (article)]

Langue / Language

Allemand
Revue : Anglais

Editeur / Publisher

Schaper, Alfeld, ALLEMAGNE  (1971) (Revue)

Mots-clés d'auteur / Author Keywords

intersexuality ; horse ; male pseudohermaphroditism ; sex reversal syndrome ;

Localisation / Location

INIST-CNRS, Cote INIST : 27195, 35400015974695.0020