Titre du document / Document title

Social and emotional problems in children with neurofibromatosis type 1 : Evidence and proposed interventions

Auteur(s) / Author(s)

JOHNSON N. S. ⁽¹⁾ ; SAAL H. M. ⁽¹⁾ ; LOVELL A. M. ⁽¹⁾ ; SCHORRY E. K. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Division of Human Genetics, Children's Hospital Medical Center, Cincinnati, Ohio, ETATS-UNIS

Résumé / Abstract

Objective: To describe social and emotional problems in children and adolescents with neurofibromatosis type 1 (NF1) and propose interventions. Our hypothesis is that children with NFI will have significantly more social and emotional problems, compared with their unaffected siblings and children in the general population. Study design: Forty-three children with NFI and 22 unaffected siblings (ages 5 to 18 years) were assessed with a standardized test completed by parents and teachers (the Child Behavior Checklist). Results: As with other aspects of NF1, there was variable expressivity. However, when rated by parents, children with NF1 had significantly more problems in comparison with test norms or unaffected siblings on 7 of 8 scales: Social Problems, Attention Problems, Anxiety/Depression, Withdrawal, Thought Problems, Somatic Complaints, and Aggressive Behavior. Children with NF1 also scored lower than unaffected siblings on measures assessing sports and other activities. Teachers reported fewer differences. Conclusions: We propose interventions in the form of information for parents ; early screening and treatment for speech, motor, and cognitive problems ; and an increased level of intervention to prevent and treat psychologic problems, including systematic screening with standardized tests.

Revue / Journal Title

The Journal of pediatrics   ISSN 0022-3476   CODEN JOPDAB 

Source / Source

1999, vol. 134, n^o6, pp. 767-772 (25 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, New York, NY, ETATS-UNIS  (1932) (Revue)

Mots-clés anglais / English Keywords

Neurofibromatosis Recklinghausen ; Prognosis ; Social adjustment ; Behavioral disorder ; Psychological effect ; Learning disability ; Child ; Psychomotor development ; Cognitive disorder ; Prevalence ; Human ; Nervous system diseases ; Benign neoplasm ; Phacomatosis ; Skin disease ; Genetic disease ;

Mots-clés français / French Keywords

Neurofibromatose Recklinghausen ; Pronostic ; Adaptation sociale ; Trouble comportement ; Effet psychologique ; Trouble apprentissage ; Enfant ; Développement psychomoteur ; Trouble cognition ; Prévalence ; Homme ; Système nerveux pathologie ; Tumeur bénigne ; Phacomatose ; Peau pathologie ; Maladie héréditaire ;

Mots-clés espagnols / Spanish Keywords

Neurofibromatosis Recklinghausen ; Pronóstico ; Adaptación social ; Trastorno conducta ; Efecto psicológico ; Trastorno aprendizaje ; Niño ; Desarrollo psicomotor ; Trastorno cognitivo ; Prevalencia ; Hombre ; Sistema nervioso patología ; Tumor benigno ; Facomatosis ; Piel patología ; Enfermedad hereditaria ;

Localisation / Location

INIST-CNRS, Cote INIST : 2061, 35400008481419.0200