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Titre du document / Document title

Adherence therapy for people with schizophrenia: European multicentre randomised controlled trial

Auteur(s) / Author(s)

GRAY Richard (1) ; LEESE Morven (1) ; BINDMAN Jonathan (1) ; BECKER Thomas (2) ; BURTI Lorenzo (3) ; DAVID Anthony (4) ; GOURNAY Kevin (5) ; KIKKERT Martijn (5) ; KOETER Maarten (5) ; PUSCHNER Bernd (6) ; SCHENE Aart (5) ; THORNICROFT Graham (1) ; TANSELLA Michele (5) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Health Services Research Department, Institute of Psychiatry, King's College London, ROYAUME-UNI
(2) Department of Psychiatry II, University of Ulm, BKH Günzburg, ALLEMAGNE
(3) Department of Medicine and Public Health, Policlinico G.B. Rossi, Verona, ITALIE
(4) Section of Cognitive Neuropsychiatry, ROYAUME-UNI
(5) Academic Medical Center, Department of Psychiatry, University of Amsterdam, PAYS-BAS
(6) Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology University of Verona, ITALIE

Résumé / Abstract

Background There is equivocal evidence of the effectiveness of adherence therapy in improving treatment adherence and clinical outcomes for people with schizophrenia. Aims To evaluate the effectiveness of adherence therapy in improving quality of life for people with schizophrenia. Method A 52-week, single-blind, multicentre randomised controlled trial of the effectiveness of adherence therapy. Participants were individually randomised to receive eight sessions of adherence therapy or health education. Assessments were undertaken at baseline and at 52-week follow-up. Results Adherence therapy was no more effective than health education in improving quality of life. Conclusions This effectiveness trial provides evidence for the lack of effect of adherence therapy in people with schizophrenia with recent clinical instability treated in ordinary clinical settings.

Revue / Journal Title

British journal of psychiatry    ISSN  0007-1250   CODEN BJPYAJ 

Source / Source

2006, vol. 189, noDEC, pp. 508-514 [7 page(s) (article)] (33 ref.)

Langue / Language

Anglais

Editeur / Publisher

Maney, Leeds, ROYAUME-UNI  (1963) (Revue)

Mots-clés anglais / English Keywords

Psychosis

;

Human

;

Multicenter study

;

Clinical trial

;

Public health

;

Europe

;

Therapy

;

Treatment

;

Treatment compliance

;

Schizophrenia

;

Mots-clés français / French Keywords

Psychose

;

Homme

;

Etude multicentrique

;

Essai clinique

;

Santé publique

;

Europe

;

Thérapie

;

Traitement

;

Observance thérapeutique

;

Schizophrénie

;

Mots-clés espagnols / Spanish Keywords

Psicosis

;

Hombre

;

Estudio multicéntrico

;

Ensayo clínico

;

Salud pública

;

Europa

;

Terapia

;

Tratamiento

;

Observancia del tratamiento

;

Esquizofrenia

;

Localisation / Location

INIST-CNRS, Cote INIST : 3999, 35400015949762.0060

Nº notice refdoc (ud4) : 18329264



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