Titre du document / Document title

DEPRES II (Depression Research in European Society II) : A patient survey of the symptoms, disability and current management of depression in the community

Auteur(s) / Author(s)

TYLEE A. ⁽¹⁾ ; GASTPAR M. ⁽¹⁾ ; LEPINE J.-P. ⁽¹⁾ ; MENDLEWICZ J. ⁽¹⁾ ; COMMITTEE O. B. O. T. D. S. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Institute of Psychiatry, De Crespigny Park, London, ROYAUME-UNI

Résumé / Abstract

The first pan-European survey of depression in the community (DEPRES I) demonstrated that 17% of the general population suffer from depression (major depression, minor depression, or depressive symptoms). This article describes findings from a second phase of DEPRES (DEPRES II), in which detailed interviews based on a semi-structured questionnaire (78 questions) were conducted with 1884 DEPRES I participants who had suffered from depression and who consulted a healthcare professional about their symptoms during the previous 6 months. The mean time from onset of depression was 45 months, and the most commonly experienced symptoms during the latest period were low mood (76%), tiredness (73%) and sleep problems (63%). During the previous 6 months, respondents had been unable to undertake normal activities because of their depression for a mean of 30 days, and a mean of 20 days of work had been lost to depression by those in paid employment. Approximately one-third of respondents (30%) had received an antidepressant during the latest period of depression. Significantly more respondents given a selective serotonin reputake inhibitor found that their treatment made them feel more like their normal self than those given a tricyclic antidepressant, and fewer reported treatment-related concentration lapses, weight problems, and heavy-headedness (all P < 0.05). Approximately two-thirds of respondents (70%) had received no antidepressant therapy during the latest period of depression, and prescription of benzodiazepines alone, which are not effective against depression, was widespread (17%). There is a need for education of healthcare professionals to encourage appropriate treatment of depression.

Revue / Journal Title

International clinical psychopharmacology   ISSN 0268-1315 

Source / Source

1999, vol. 14, n^o3, pp. 139-151 (28 ref.)

Langue / Language

Anglais

Editeur / Publisher

Lippincott Williams & Wilkins, Hagerstown, MD, ETATS-UNIS  (1986) (Revue)

Mots-clés anglais / English Keywords

Antidepressant agent ; Psychotropic ; Use ; Depression ; Mood disorder ; Symptomatology ; Evolution ; Human ; Epidemiology ; Public health ; Europe ; Chemotherapy ; Medical prescription ; Treatment efficiency ;

Mots-clés français / French Keywords

Antidépresseur ; Psychotrope ; Utilisation ; Etat dépressif ; Trouble humeur ; Symptomatologie ; Evolution ; Homme ; Epidémiologie ; Santé publique ; Europe ; Chimiothérapie ; Prescription médicale ; Efficacité traitement ;

Mots-clés espagnols / Spanish Keywords

Antidepresor ; Psicotropo ; Utilización ; Estado depresivo ; Trastorno humor ; Sintomatología ; Evolución ; Hombre ; Epidemiología ; Salud pública ; Europa ; Quimioterapia ; Prescripción médica ; Eficacia tratamiento ;

Localisation / Location

INIST-CNRS, Cote INIST : 21187, 35400008483043.0010