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Titre du document / Document title

Assessment of feminization of male fish in english rivers by the environment agency of england and wales

Auteur(s) / Author(s)

GROSS-SOROKIN Melanie Y. ; ROAST Stephen D. ; BRIGHTY Geoffrey C. ;

Résumé / Abstract

In recent years there has been considerable concern over the ability of substances discharged into the environment to disrupt the normal endocrine function of wildlife. In particular, the apparent widespread feminization of male fish in rivers has received significant attention from regulators in the United Kingdom, the United States, Europe, and Japan. The U.K. and European epidemiological data sets have demonstrated that the occurrence of feminized fish is associated with effluent discharges and that the incidence and severity is positively correlated with the proportion of treated sewage effluent in receiving waters. Although weakly estrogenic substances may contribute to the overall effect, studies have concluded that steroid estrogens are the principal and most potent estrogenic components of domestic sewage. Extensive laboratory data sets confirm that steroid estrogens are capable of eliciting the effects observed in wild fish at concentrations that have been measured in effluents and in the environment. Based on evaluation of the available information, the Environment Agency (England and Wales) has concluded that the weight of evidence for endocrine disruption in fish is sufficient to develop a risk management strategy for estro-genically active effluents that discharge to the aquatic environment.

Revue / Journal Title

Environmental health perspectives. Supplements    ISSN  1078-0475   CODEN EHPSEO 

Source / Source

2006, vol. 114, no1, pp. 147-151 [5 page(s) (article)]

Langue / Language


Editeur / Publisher

National Institute of Environmental Health Sciences, Research Triangle Park, NC, ETATS-UNIS  (1993-2002) (Revue)

Mots-clés d'auteur / Author Keywords

endocrine disruption












risk assessment


steroid estrogen


Localisation / Location

INIST-CNRS, Cote INIST : 17072 S, 35400013882015.0220

Nº notice refdoc (ud4) : 17943521

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