Titre du document / Document title

Assessment of the Heidelberg Retina Tomograph in the detection of sight-threatening diabetic maculopathy

Auteur(s) / Author(s)

ZAMBARAKJI H. J. ⁽¹⁾ ; BUTLER T. K. H. ⁽¹⁾ ; VERNON S. A. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Ophthalmology, Queen's Medical Centre, University Hospital, Nottingham, ROYAUME-UNI

Résumé / Abstract

Purpose: To assess the potential role of the Heidelberg Retina Tomograph (HRT) in screening for sight-threatening macular oedema in diabetes. Methods One hundred and thirty-one eyes of 81 consecutive diabetic patients who fitted the inclusion criteria were included in the study. On HRT, the volume above the reference plane bound within a 2 mm diameter circle centred at the fovea was measured. The volumetric indices were compared with the mean measurement index in a group of 20 age-matched controls (mean score = 1, mean +2 SD score = 1.8). We also assessed the sensitivity of the subjective analysis of the intensity image and the addition of the three-dimensional map to the intensity image for detecting macular oedema and clinically significant macular oedema (CSMO). Results One hundred and twelve eyes of 71 patients had a corrected Snellen visual acuity of 6/9 or better. When considering eyes with 6/9 or better vision only, the system's sensitivity for detecting CSMO was 58.33% 'per eye' examined, and 81.82% 'per patient' examined using a cut-off volumetric index of 1.8. In our study eyes with 6/9 or better vision, we found a 21% prevalence of CSMO. The predictive values of a positive test were 38.89% and 45% (cut-off score 1.8, 'per eye' and 'per patient' respectively) for CSMO. The predictive values of a negative test were 86.84% and 90.48% (cut-off score 1.8,'per eye' and 'per patient' respectively) for CSMO. Conclusions The volumetric assessment of diabetic maculopathy by HRT is a potentially useful method for screening eyes at risk. A larger group of patients with a greater number of eyes with minimal or no maculopathy is required to establish the specificity of this technique.

Revue / Journal Title

Eye   ISSN 0950-222X   CODEN EYEEEC 

Source / Source

1999, vol. 13 (2), pp. 136-144 (29 ref.)

Langue / Language

Anglais

Editeur / Publisher

Nature Publishing Group, Basingstoke, ROYAUME-UNI  (1987) (Revue)

Mots-clés anglais / English Keywords

Diabetes mellitus ; Edema ; Macula ; Medical screening ; Tomograph ; Technique ; Evaluation ; Human ; Endocrinopathy ; Eye disease ; Maculopathy ;

Mots-clés français / French Keywords

Diabète ; Oedème ; Macula ; Dépistage ; Tomographe ; Technique ; Evaluation ; Homme ; Endocrinopathie ; Oeil pathologie ; Maculopathie ;

Mots-clés espagnols / Spanish Keywords

Diabetes ; Edema ; Mácula ; Descubrimiento ; Tomógrafo ; Técnica ; Evaluación ; Hombre ; Endocrinopatía ; Ojo patología ; Maculopatía ;

Localisation / Location

INIST-CNRS, Cote INIST : 21076, 35400008431182.0020