Titre du document / Document title

The role of nausea in taste avoidance learning in rats and shrews

Auteur(s) / Author(s)

PARKER Linda A. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, N2L 3C5, CANADA

Résumé / Abstract

When paired with a novel flavoured solution, the injection of an emetic drug, such as lithium chloride, produces avoidance of that solution in both non-emetic rats and in emetic shrews. On the other hand, the pairing of a novel flavour with a drug with rewarding properties results in conditioned taste avoidance in rats, but in conditioned taste preference in shrews. It, therefore, appears that nausea may be necessary for the establishment of conditioned taste avoidance in the emetic shrew, but not in the non-emetic rat. Indeed, pre-treatment with the anti-emetic agents, ondansetron or Δ⁹-tetrahydrocannabinol, interferes with the establishment of lithium-induced conditioned taste avoidance in the shrew, but does not even attenuate the establishment of lithium-induced conditioned taste avoidance in the rat. The results of a number of studies suggest that the nature of flavour-drug associations varies on the basis of the emetic capacity of the species.

Revue / Journal Title

Autonomic neuroscience : basic & clinical   ISSN 1566-0702 

Source / Source

Congrès
Pavlov centenary symposium: integrative physiology and behaviour, Saint Petersburg , RUSSIE, FEDERATION DE (06/2004)
2006, vol. 125, n^o 1-2 (118 p.)  [Document : 8 p.] (1 p.3/4), pp. 34-41 [8 page(s) (article)]

Langue / Language

Anglais

Editeur / Publisher

Elsevier, Amsterdam, PAYS-BAS  (2000) (Revue)

Mots-clés anglais / English Keywords

Insectivora ; Vertebrata ; Mammalia ; Rodentia ; Nootropic agent ; Psychotropic ; Neurotransmitter ; Acquisition process ; Gustative system ; Gustation ; Animal ; Autonomic nervous system ; Suncus murinus ; Rat ; Lithium ; Serotonin ; Ondansetron ; Cannabinoid ; Learning ; Avoidance ; Taste ;

Mots-clés français / French Keywords

Insectivora ; Vertebrata ; Mammalia ; Rodentia ; Nootrope ; Psychotrope ; Neurotransmetteur ; Processus acquisition ; Système gustatif ; Gustation ; Animal ; Système nerveux autonome ; Suncus murinus ; Rat ; Lithium ; Sérotonine ; Ondansétron ; Cannabinoïde ; Apprentissage ; Evitement ; Saveur ;

Mots-clés espagnols / Spanish Keywords

Insectivora ; Vertebrata ; Mammalia ; Rodentia ; Nootropo ; Psicotropo ; Neurotransmisor ; Proceso adquisición ; Sistema gustativo ; Gusto ; Animal ; Sistema nervioso autónomo ; Suncus murinus ; Rata ; Litio ; Serotonina ; Ondansetrón ; Canabinoide ; Aprendizaje ; Evitación ; Sabor ;

Mots-clés d'auteur / Author Keywords

Shrew ; Rat ; Suncus murinus ; Insectivore ; Omnivore ; Learning ; Taste avoidance ; Taste aversion ; A9-tetrahydrocannabinol ; Cannabinoids ; Ondansetron ; Serotonin ; Lithium ;

Localisation / Location

INIST-CNRS, Cote INIST : 18294, 35400014263819.0060