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Titre du document / Document title

Magnetic field exposure and long-term survival among children with leukaemia

Auteur(s) / Author(s)

FOLIART D. E. (1) ; POLLOCK B. H. (2) ; MEZEI G. (3) ; IRIYE R. (4) ; SILVA J. M. (4) ; EBI K. L. (5) ; KHEIFETS L. (6) ; LINK M. P. (7) ; KAVET R. (3) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Public Health Institute, 555 12th St, Oakland, CA 94607, ETATS-UNIS
(2) Center for Epidemiology and Biostotistics, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, ETATS-UNIS
(3) Electric Power Research Institute (EPRI), 3412 Hillview Avenue, Palo Alto, CA 94304, ETATS-UNIS
(4) Enertech Consultants, 300 Orchard City Drive, Suite 132, Compbell, CA 95008, ETATS-UNIS
(5) Exponent Health Sciences Group, 1800 Diagonal Road, Suite 300, Alexandria, VA 22314, ETATS-UNIS
(6) Department of Epidemiology, School of Public Health, University of California, Los Angeles, 650 Charles E Young Drive South, Los Angeles, CA 90095, ETATS-UNIS
(7) Department of Pediatrics, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, ETATS-UNIS

Résumé / Abstract

We examined the association between magnetic field (MF) exposure and survival among children with acute lymphoblastic leukaemia (ALL) treated at 51 Pediatric Oncology Group centres between 1996 and 2001. Of 1672 potentially eligible children under treatment, 482 (29%) participated and personal 24-h MF measurements were obtained from 412 participants. A total of 386 children with ALL and 361 with B-precursor ALL were included in the analysis of event-free survival (time from diagnosis to first treatment failure, relapse, secondary malignancy, or death) and overall survival. After adjustment for risk group and socioeconomic status, the event-free survival hazard ratio (HR) for children with measurements ≥0.3μT was 1.9 (95% confidence interval (Cl) 0.8, 4.9), compared to <0.1 μT. For survival. elevated HRs were found for children exposed to ≥0.3μT (multivariate HR=4.5, 95% Cl 1.5-13.8) but based on only four deaths among 19 children. While risk was increased among children with exposures above 0.3 μT, the small numbers limited inferences for this finding.

Revue / Journal Title

British journal of cancer    ISSN  0007-0920   CODEN BJCAAI 

Source / Source

2006, vol. 94, no1, pp. 161-164 [4 page(s) (article)] (17 ref.)

Langue / Language

Anglais

Editeur / Publisher

Nature Publishing Group, Basingstoke, ROYAUME-UNI  (1947) (Revue)

Mots-clés anglais / English Keywords

Lymphoproliferative syndrome

;

Malignant hemopathy

;

Human

;

Acute

;

Cancerology

;

Electromagnetic field

;

Child

;

Survival

;

Long term

;

Acute leukemia

;

Exposure

;

Magnetic field

;

Acute lymphocytic leukemia

;

Mots-clés français / French Keywords

Lymphoprolifératif syndrome

;

Hémopathie maligne

;

Homme

;

Aigu

;

Cancérologie

;

Champ électromagnétique

;

Enfant

;

Survie

;

Long terme

;

Leucémie aiguë

;

Exposition

;

Champ magnétique

;

Leucémie lymphoblastique

;

Mots-clés espagnols / Spanish Keywords

Linfoproliferativo síndrome

;

Hemopatía maligna

;

Hombre

;

Agudo

;

Cancerología

;

Campo electromagnético

;

Niño

;

Sobrevivencia

;

Largo plazo

;

Leucemia aguda

;

Exposición

;

Campo magnético

;

Leucemia linfoblástica

;

Mots-clés d'auteur / Author Keywords

electromagnetic fields

;

leukaemia

;

lymphoblastic leukaemia

;

acute childhood leukaemia

;

Localisation / Location

INIST-CNRS, Cote INIST : 6925, 35400015346613.0270

Nº notice refdoc (ud4) : 17666177



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