Titre du document / Document title

Multifactorial approach and adherence to prescribed oral medications in patients with type 2 diabetes

Auteur(s) / Author(s)

MATED J. F. ^{(1 2)} ; GIL-GUILLEN V. F. ^{(1 3)} ; MATEO E. ⁽¹⁾ ; OROZCO D. ^{(1 4)} ; CARBAYO J. A. ^{(1 5)} ; MERINO J. ^{(1 6)} ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Primary Care at UMH, Alicante, ESPAGNE
⁽²⁾ Rafelcofer Health Centre, Valencia, ESPAGNE
⁽³⁾ Monovar Health Centre, ESPAGNE
⁽⁴⁾ Petrer Health Centre, Alicante, ESPAGNE
⁽⁵⁾ Lipids Unit, Clínica Virgen del Rosario, Albacete, ESPAGNE
⁽⁶⁾ Internal Medicine Department at University Hospital San Juan, Alicante, ESPAGNE

Résumé / Abstract

The aims of this study were to assess adherence to oral hypoglycaemic/cardiovascular drugs and determine non-adherence predictors in type 2 diabetes patients. It was designed as a population-based cross-sectional study in which 90 patients from a primary care setting were studied. Pill count and self-report methods were used to measure adherence. Logistic regression analysis was performed to predict factors related to non-adherence. Adequate adherence to all drugs was found in 29 patients (35.4%; 95% confidence interval (CI) 25.0-45.7). Variables associated with non-adherence were HbA_1c odds ratio (OR) 2.32 (95% CI: 1.09-4.95), systolic blood pressure OR 1.68 (95% CI: 1.08-2.62), total cholesterol OR 1.34 (95% CI: 1.08-1.66), number of pills OR 1.80 (95% CI: 1.26-2.55) and duration of disease OR 0.44 (CI 95%: 0.24-0.83). In conclusion, one in three patients had adequate adherence. Factors associated with non-adherence were duration of disease, complexity of drug regimen and inadequate control of cardiovascular risk factors.

Revue / Journal Title

International journal of clinical practice   ISSN 1368-5031 

Source / Source

2006, vol. 60, n^o4, pp. 422-428 [7 page(s) (article)] (30 ref.)

Langue / Language

Anglais

Editeur / Publisher

Blackwell, Oxford, ROYAUME-UNI  (1997) (Revue)

Mots-clés anglais / English Keywords

Metabolic diseases ; Endocrinopathy ; Medicine ; Risk factor ; Cardiovascular disease ; Treatment ; Drug ; Patient ; Human ; Oral administration ; Attitude ; Chemotherapy ; Drug compliance ; Treatment compliance ; Type 2 diabetes ;

Mots-clés français / French Keywords

Métabolisme pathologie ; Endocrinopathie ; Polymédication ; Médecine ; Facteur risque ; Appareil circulatoire pathologie ; Traitement ; Médicament ; Malade ; Homme ; Voie orale ; Attitude ; Chimiothérapie ; Observance médicamenteuse ; Observance thérapeutique ; Diabète type 2 ;

Mots-clés espagnols / Spanish Keywords

Metabolismo patología ; Endocrinopatía ; Medicina ; Factor riesgo ; Aparato circulatorio patología ; Tratamiento ; Medicamento ; Enfermo ; Hombre ; Vía oral ; Actitud ; Quimioterapia ; Observancia de la medicación ; Observancia del tratamiento ; Diabetes de tipo 2 ;

Mots-clés d'auteur / Author Keywords

Patient compliance ; diabetes mellitus ; type 2 ; drug therapy ; polypharmacy ; cardiovascular diseases ; risk factors ;

Localisation / Location

INIST-CNRS, Cote INIST : 15561, 35400015296966.0090