Titre du document / Document title

Conjunctival deposits as the first sign of systemic sarcoidosis in a pediatric patient

Auteur(s) / Author(s)

CACA I. ; ÜNLÜ K. ; BÜYÜKBAYRAM H. ; ARI S. ;

Résumé / Abstract

PURPOSE. Sarcoidosis is an inflammatory disease of unknown cause, characterized by noncaseating granulomas. In this study, the authors present a sarcoidosis patient without systemic signs diagnosed by histopathologic analysis of conjunctival deposits. METHODS. A 10-year-old girl had bilateral, focal, multilobular, multiple pale yellow deposits in bulbar conjunctiva for a year. In the patient's biomicroscopic examination, numerous 0.50-to 2-mm diameter pale yellow deposits were determined in both bulbar conjunctivas. The patient had no other systemic or ocular complaints. A conjunctival biopsy was performed. RESULTS. The biopsy specimens showed noncaseating granulomas with prominent asteroid bodies. Serum angiotensin-converting enzyme levels were increased in the patient. Conjunctival deposits were the first manifestation of sarcoidosis in the patient and the diagnosis of sarcoidosis was confirmed with a conjunctival biopsy. CONCLUSIONS. To the authors' knowledge, this is the second study that reports a sarcoidosis patient with non-systemic involvement diagnosed after histopathologic analysis of conjunctival deposits.

Revue / Journal Title

European Journal of Ophthalmology   ISSN 1120-6721 

Source / Source

2006, vol. 16, n^o1, pp. 168-170 [3 page(s) (article)]

Langue / Language

Anglais

Editeur / Publisher

Wichtig, Milano, ITALIE  (1991) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 22516, 35400013246260.0270