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Titre du document / Document title

Allergic disease and sensitization in Steiner school children

Auteur(s) / Author(s)

PARSIFAL Study Group
FLÖISTRUP Helen (1 2) ; SWARTZ Jackie (3) ; BERGSTRÖM Anna (1) ; ALM Johan S. (4) ; SCHEYNIUS Annika (5) ; VAN HAGE Marianne (6) ; WASER Marco (7) ; BRAUN-FAHRLÄNDER Charlotte (7) ; SCHRAM-BIJKERK Dieneke (8) ; HUBER Machteld (9) ; ZUTAVERN Anne (10) ; VON MUTIUS Erika (9) ; ÜBLAGGER Ellen (11) ; RIEDLER Josef (12) ; MICHAELS Karin B. (13) ; PERSHAGEN Göran (1 14) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Institute of Environmental Medicine, SUEDE
(2) Centre for Allergy Research, Karolinska Institutet, Stockholm, SUEDE
(3) Vidar Clinic, Jäma
(4) Sachs' Children's Hospital, Stockholm Söder Hospital, SUEDE
(5) Department of Medicine, Clinical Allergy Research Unit, Karolinska Institute and University Hospital, Stockholm, SUEDE
(6) Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institute and University Hospital, Stockholm, SUEDE
(7) Department of Environment and Health, Institute of Social and Preventive Medicine, University of Basel, SUEDE
(8) Institute for Risk Assessment Sciences, Utrecht University, PAYS-BAS
(9) Louis Bolk Institute, Driebergen, PAYS-BAS
(10) Dr von Hauner Children's Hospital, University of Munich, ALLEMAGNE
(11) Department of Paediatric Pulmonology and Allergology, Children's Hospital, Salzburg, AUTRICHE
(12) Children's Hospital Schwarzach, AUTRICHE
(13) Brigham and Women's Hospital, Harvard Medical School, and Department of Epidemiology, Harvard School of Public Health, Boston, ETATS-UNIS
(14) Department of Occupational and Environmental Health, Stockholm County Council, SUEDE

Résumé / Abstract

Background: The anthroposophic lifestyle has several features of interest in relation to allergy: for example, a restrictive use of antibiotics and certain vaccinations. In a previous Swedish study, Steiner school children (who often have an anthroposophic lifestyle) showed a reduced risk of atopy, but specific protective factors could not be identified. Objective: To investigate factors that may contribute to the lower risk of allergy among Steiner school children. Methods: Cross-sectional multicenter study including 6630 children age 5 to 13 years (4606 from Steiner schools and 2024 from reference schools) in 5 European countries. Results: The prevalence of several studied outcomes was lower in Steiner school children than in the reference group. Overall, there were statistically significant reduced risks for rhinoconjunctivitis, atopic eczema, and atopic sensitization (allergen-specific IgE ≥0.35 kU/L), with some heterogeneity between the countries. Focusing on doctor-diagnosed disease, use of antibiotics during first year of life was associated with increased risks of rhinoconjunctivitis (odds ratio [OR], 1.97; 95% CI, 1.26-3.08), asthma (OR, 2.79; 95% CI, 2.03-3.83), and atopic eczema (OR, 1.63; 95% CI, 1.22-2.17). Early use of antipyretics was related to an increased risk of asthma (OR, 1.54; 95% CI, 1.11-2.13) and atopic eczema (OR, 1.32; 95% CI, 1.02-1.71). Children having received measles, mumps, and rubella vaccination showed an increased risk of rhinoconjunctivitis, whereas measles infection was associated with a lower risk of IgE-mediated eczema. Conclusion: Certain features of the anthroposophic lifestyle, such as restrictive use of antibiotics and antipyretics, are associated with a reduced risk of allergic disease in children.

Revue / Journal Title

Journal of allergy and clinical immunology    ISSN  0091-6749   CODEN JACIBY 

Source / Source

2006, vol. 117, no1, pp. 59-66 [8 page(s) (article)] (30 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, New York, NY, ETATS-UNIS  (1971) (Revue)

Mots-clés anglais / English Keywords

Lung disease

;

Bronchus disease

;

Feeding

;

Obstructive pulmonary disease

;

Respiratory disease

;

Immunopathology

;

Immunology

;

Infection

;

Viral disease

;

Human

;

Prevention

;

Vaccination

;

Nutrition

;

Diet

;

Antipyretic

;

Antibiotic

;

Measles

;

Life style

;

School age

;

Asthma

;

Child

;

Sensitization

;

Allergy

;

Mots-clés français / French Keywords

Poumon pathologie

;

Bronche pathologie

;

Alimentation

;

Bronchopneumopathie obstructive

;

Appareil respiratoire pathologie

;

Immunopathologie

;

Immunologie

;

Infection

;

Virose

;

Homme

;

Prévention

;

Vaccination

;

Nutrition

;

Régime alimentaire

;

Antipyrétique

;

Antibiotique

;

Rougeole

;

Mode de vie

;

Age scolaire

;

Asthme

;

Enfant

;

Sensibilisation

;

Allergie

;

Mots-clés espagnols / Spanish Keywords

Pulmón patología

;

Bronquio patología

;

Alimentación

;

Broncopneumopatía obstructiva

;

Aparato respiratorio patología

;

Inmunopatología

;

Inmunología

;

Infección

;

Virosis

;

Hombre

;

Prevención

;

Vacunación

;

Nutrición

;

Régimen alimentario

;

Antipirético

;

Antibiótico

;

Sarampión

;

Modo de vida

;

Edad escolar

;

Asma

;

Niño

;

Sensibilización

;

Alergia

;

Mots-clés d'auteur / Author Keywords

Allergy

;

anthroposophic lifestyle

;

antibiotics

;

antipyretics. asthma

;

biodynamic diet

;

measles

;

sensitization

;

vaccination

;

Localisation / Location

INIST-CNRS, Cote INIST : 2059, 35400013451639.0090

Nº notice refdoc (ud4) : 17433217



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