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Titre du document / Document title

Estimates of HIV incidence among persons testing for hiv using the sensitive/less sensitive enzyme immunoassy, New York City, 2001

Auteur(s) / Author(s)

NASH Denis (1) ; BENNANI Yussef (1) ; RAMASWAMY Chitra (1) ; TORIAN Lucia (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) New York City Department of Health and Mental Hygiene, Bureau of HIV/AIDS, HIV Surveillance and Epidemiology Program, New York, NY, ETATS-UNIS

Résumé / Abstract

Background: Estimates of the incidence of HIV infection among persons testing for HIV can be derived by applying a newly available serologic test to the diagnostic specimen of HIV-positive persons. Such estimates would enhance the targeting of HIV prevention resources and provide a sensitive outcome measure for prevention program evaluation. The goal of this investigation was to estimate the incidence of HIV infection among persons testing for HIV in New York City. Methods: The study population consisted of persons testing for HIV in public settings in New York City during 2001 (n = 114,703). We applied a less sensitive enzyme immunoassay (LS-EIA) (Vironostika, BioMerieux, Durham, NC) to the diagnostic blood specimen of 1022 persons in whom HIV (non-AIDS) had been diagnosed for the first time in 2001. The distribution of transmission risk among HIV-negative persons-men who have sex with men (MSM), injection drug users (IDUs), heterosexuals-from a large telephone health survey was used to generate denominators for transmission risk groups. Results: The 1022 persons tested by the LS-EIA represented 27% of all persons in whom HIV (non-AIDS) had been diagnosed in New York City during 2001. The incidence of HIV was estimated to be 0.29% per year (95% CI: 0.20-0.38), and was significantly higher for men than women (rate ratio 3.6, 95% CI: 2.6-5.1), and HIV incidence increased with age. Male IDU and MSM testers had the highest HIV incidence rates: 2.7% per year (95% CI: 2.3-3.1) and 2.5% per year (95% CI: 2.1-2.8), respectively. Conclusions: Male IDUs and MSM may be good candidates for intensified targeting of HIV prevention resources in New York City.

Revue / Journal Title

Journal of acquired immune deficiency syndromes    ISSN  1525-4135 

Source / Source

2005, vol. 39, no1, pp. 102-111 [10 page(s) (article)] (29 ref.)

Langue / Language

Anglais

Editeur / Publisher

Lippincott Williams & Wilkins, Hagerstown, MD, ETATS-UNIS  (1999) (Revue)

Mots-clés anglais / English Keywords

Immunopathology

;

Infection

;

Viral disease

;

Immune deficiency

;

America

;

North America

;

United States

;

Virus

;

Retroviridae

;

Lentivirus

;

AIDS

;

Virology

;

Microbiology

;

Enzyme immunoassay

;

New York

;

Enzyme

;

Epidemiology

;

Incidence

;

Human immunodeficiency virus

;

Human

;

Mots-clés français / French Keywords

Immunopathologie

;

Infection

;

Virose

;

Immunodéficit

;

Amérique

;

Amérique du Nord

;

Etats Unis

;

Virus

;

Retroviridae

;

Lentivirus

;

SIDA

;

Virologie

;

Microbiologie

;

Méthode immunoenzymatique

;

New York

;

Enzyme

;

Epidémiologie

;

Incidence

;

Virus immunodéficience humaine

;

Homme

;

Mots-clés espagnols / Spanish Keywords

Inmunopatología

;

Infección

;

Virosis

;

Inmunodeficiencia

;

America

;

America del norte

;

Estados Unidos

;

Virus

;

Retroviridae

;

Lentivirus

;

SIDA

;

Virología

;

Microbiología

;

Método inmunoenzimático

;

Nueva York

;

Enzima

;

Epidemiología

;

Incidencia

;

Human immunodeficiency virus

;

Hombre

;

Mots-clés d'auteur / Author Keywords

HIV

;

surveillance

;

less sensitive enzyme immunoassay

;

STARHS

;

HIV incidence

;

Localisation / Location

INIST-CNRS, Cote INIST : 21576, 35400012984044.0140

Nº notice refdoc (ud4) : 16756628



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