Titre du document / Document title
Estimates of HIV incidence among persons testing for hiv using the sensitive/less sensitive enzyme immunoassy, New York City, 2001
Auteur(s) / Author(s)
NASH Denis (1) ;
BENNANI Yussef (1) ;
RAMASWAMY Chitra (1) ;
TORIAN Lucia (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) New York City Department of Health and Mental Hygiene, Bureau of HIV/AIDS, HIV Surveillance and Epidemiology Program, New York, NY, ETATS-UNIS
Résumé / Abstract
Background: Estimates of the incidence of HIV infection among persons testing for HIV can be derived by applying a newly available serologic test to the diagnostic specimen of HIV-positive persons. Such estimates would enhance the targeting of HIV prevention resources and provide a sensitive outcome measure for prevention program evaluation. The goal of this investigation was to estimate the incidence of HIV infection among persons testing for HIV in New York City. Methods: The study population consisted of persons testing for HIV in public settings in New York City during 2001 (n = 114,703). We applied a less sensitive enzyme immunoassay (LS-EIA) (Vironostika, BioMerieux, Durham, NC) to the diagnostic blood specimen of 1022 persons in whom HIV (non-AIDS) had been diagnosed for the first time in 2001. The distribution of transmission risk among HIV-negative persons-men who have sex with men (MSM), injection drug users (IDUs), heterosexuals-from a large telephone health survey was used to generate denominators for transmission risk groups. Results: The 1022 persons tested by the LS-EIA represented 27% of all persons in whom HIV (non-AIDS) had been diagnosed in New York City during 2001. The incidence of HIV was estimated to be 0.29% per year (95% CI: 0.20-0.38), and was significantly higher for men than women (rate ratio 3.6, 95% CI: 2.6-5.1), and HIV incidence increased with age. Male IDU and MSM testers had the highest HIV incidence rates: 2.7% per year (95% CI: 2.3-3.1) and 2.5% per year (95% CI: 2.1-2.8), respectively. Conclusions: Male IDUs and MSM may be good candidates for intensified targeting of HIV prevention resources in New York City.
Revue / Journal Title
Journal of acquired immune deficiency syndromes
ISSN
1525-4135
Source / Source
2005, vol. 39, n
o1, pp. 102-111 [10 page(s) (article)] (29 ref.)
Langue / Language
Anglais
Editeur / Publisher
Lippincott Williams & Wilkins, Hagerstown, MD, ETATS-UNIS
(1999)
(Revue)
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Localisation / Location
INIST-CNRS, Cote INIST : 21576, 35400012984044.0140
Nº notice refdoc (ud4) : 16756628
