Titre du document / Document title

Detection of HCV-RNA in cerumen of chronically HCV-infected patients

Auteur(s) / Author(s)

BAYINDIR Yasar ⁽¹⁾ ; TAYYAR KALCIOGLU M. ⁽²⁾ ; DURMAZ Riza ⁽³⁾ ; OZTURAN Orhan ⁽²⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Infectious Diseases and Clinical Microbiology, Inonu University, Medical Faculty, Malatya, TURQUIE
⁽²⁾ Department of Otorhinolaryngology, Inonu University, Medical Faculty, Malatya, TURQUIE
⁽³⁾ Department of Medical Microbiology, Inonu University, Medical Faculty, Malatya, TURQUIE

Résumé / Abstract

Objectives/Hypothesis: Viral hepatitis C is a worldwide public health problem. Hepatitis C virus is mainly transmitted by parenteral or percutaneous route. Nonparenteral transmission, such as through sexual activity, household contact, and vertical or perinatal exposure to body fluids or secretions, can occur, which has been studied before. Cerumen, however, has not been investigated for its ability to transmit hepatitis C virus. The aim of this study is to evaluate the importance of cerumen in transmission of hepatitis C virus infection. Study Design: This study was performed on 35 patients with confirmed chronic hepatitis C virus infection. Methods: Thirty-five cerumen specimens collected from the patients with hepatitis C virus RNA in their sera were prospectively analyzed for the presence of hepatitis C virus RNA by polymerase chain reaction. Results: None of the 35 cerumen specimens were positive for hepatitis C virus RNA. Conclusion: This study showed that cerumen has no risk for transmission of hepatitis C virus infection, even in patients with high hepatitis C virus RNA serum levels; however, standard infection control precautions should be applied carefully in all examinations and surgical operations of the ears.

Revue / Journal Title

The Laryngoscope   ISSN 0023-852X   CODEN LARYA8 

Source / Source

2005, vol. 115, n^o3, pp. 508-511 [4 page(s) (article)] (24 ref.)

Langue / Language

Anglais

Editeur / Publisher

Wiley-Blackwell, Hoboken, NJ, ETATS-UNIS  (1896) (Revue)

Mots-clés anglais / English Keywords

Molecular biology ; Hepatic disease ; Digestive diseases ; Virus ; Flaviviridae ; Hepacivirus ; Viral disease ; ENT ; Transmission ; Human ; Cerumen ; RNA ; Hepatitis C virus ; Polymerase chain reaction ; Viral hepatitis C ; Infection ;

Mots-clés français / French Keywords

Biologie moléculaire ; Foie pathologie ; Appareil digestif pathologie ; Virus ; Flaviviridae ; Hepacivirus ; Virose ; ORL ; Transmission ; Homme ; Cérumen ; RNA ; Virus hépatite C ; Réaction chaîne polymérase ; Hépatite virale C ; Infection ;

Mots-clés espagnols / Spanish Keywords

Biología molecular ; Hígado patología ; Aparato digestivo patología ; Virus ; Flaviviridae ; Hepacivirus ; Virosis ; ORL ; Transmisión ; Hombre ; Cerumen ; RNA ; Hepatitis C virus ; Reacción cadena polimerasa ; Hepatitis virica C ; Infección ;

Mots-clés d'auteur / Author Keywords

Cerumen ; Hepatitis C ; polymerase chain reaction ; transmission ;

Localisation / Location

INIST-CNRS, Cote INIST : 3102, 35400012506656.0220