Titre du document / Document title

Magnesium treatment for sudden hearing loss

Auteur(s) / Author(s)

NAGERIS Ben I. ^{(1 2)} ; ULANOVSKI David ⁽¹⁾ ; ATTIAS Joseph ^{(3 4)} ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Otolaryngology-Head and Neck Surgery, Rabin Medical Center, Petah Tikva, ISRAEL
⁽²⁾ Sackler Faculty of Medicine. Tel Aviv University, Tel Aviv, ISRAEL
⁽³⁾ Institute for Clinical Neurophysiology and Audiology, Schneider Children's Medical Center of Israel, Petah Tikva, ISRAEL
⁽⁴⁾ Department of Communications Disorders, Haifa University, Haifa (Attias), ISRAEL

Résumé / Abstract

Magnesium treatment has been repeatedly shown to reduce the incidence of both temporary and permanent noise-induced hearing loss. We hypothesized that it might also improve the permanent threshold shift in patients with acute-onset hearing loss. In a prospective, randomized, double-blind, placebo-controlled trial, 28 patients with idiopathic sudden sensorineural hearing loss were treated with either steroids and oral magnesium (study group) or steroids and a placebo (control group). Compared to the controls, the magnesium-treated group had a significantly higher proportion of patients with improved hearing (>10 dB hearing level) across all frequencies tested, and a significantly greater mean improvement in all frequencies. Analysis of the individual data confirmed that more patients treated with magnesium experienced hearing improvement, and at a larger magnitude, than control subjects. Magnesium is a relatively safe and convenient adjunct to steroid treatment for enhancing the improvement in hearing, especially in the low-tone range, in patients with sudden sensorineural hearing loss.

Revue / Journal Title

The Annals of otology, rhinology & laryngology   ISSN 0003-4894   CODEN AORHA2 

Source / Source

2004, vol. 113, n^o8, pp. 672-675 [4 page(s) (article)] (20 ref.)

Langue / Language

Anglais

Editeur / Publisher

Annals Publishing Compagny, St. Louis, MO, ETATS-UNIS  (1897) (Revue)

Mots-clés anglais / English Keywords

Inorganic element ; Sudden hearing loss ; ENT ; Treatment ; Magnesium ; Chemotherapy ; Human ;

Mots-clés français / French Keywords

Elément minéral ; Surdité brusque ; ORL ; Traitement ; Magnésium ; Chimiothérapie ; Homme ;

Mots-clés espagnols / Spanish Keywords

Elemento inorgánico ; Sordera súbita ; ORL ; Tratamiento ; Magnesio ; Quimioterapia ; Hombre ;

Localisation / Location

INIST-CNRS, Cote INIST : 2077, 35400011389872.0140