Titre du document / Document title

Induced sputum and response to glucocorticoids

Auteur(s) / Author(s)

HARGREAVE F. E. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Medicine, McMaster University, Hamilton, CANADA

Résumé / Abstract

Jerry Dolovich has generated substantial new work that has had an international impact on the understanding and treatment of asthma and other airway diseases. For this, he is recognized as a Distinguished Clinician of the American Academy of Asthma, Allergy and Immunology. I have focused on some of his recent work with us using induced sputum to measure indices of airway inflammation noninvasively. The results illustrate that sputum eosinophilia (1) does not necessarily correlate with the severity of symptoms or severity of abnormalities of airway function, (2 ) does not always occur in exacerbations of asthma, and (3) may he a predictor clinical benefit to steroid treatment, which will he useful in practice. The observations imply that airway inflammation needs to be measured to understand the pathogenesis, pathophysiology, and treatment of asthma and other airway diseases.

Revue / Journal Title

Journal of allergy and clinical immunology   ISSN 0091-6749   CODEN JACIBY 

Source / Source

Congrès
Asthma and Allergy. Festschrift, Hamilton, Ontario , CANADA (24/05/1997)
1998, vol. 102, n^o 5, pp. S73-S106 (36 ref.), pp. S102-S105

Langue / Language

Anglais

Editeur / Publisher

Elsevier, New York, NY, ETATS-UNIS  (1971) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 2059, 35400007183834.0340